Paleo MR - Search Results

1

Exploring the Effect of Halogenation in a Series of Potent and Selective A_2B Adenosine Receptor Antagonists.

Prieto-Díaz R, González-Gómez M, Fojo-Carballo H, Azuaje J, El Maatougui A, Majellaro M, Loza MI, Brea J, Fernández-Dueñas V, Paleo MR, Díaz-Holguín A, Garcia-Pinel B, Mallo-Abreu A, Estévez JC, Andújar-Arias A, García-Mera X, Gomez-Tourino I, Ciruela F, Salas CO, Gutiérrez-de-Terán H, Sotelo E. Prieto-Díaz R, et al. Among authors: paleo mr. J Med Chem. 2023 Jan 12;66(1):890-912. doi: 10.1021/acs.jmedchem.2c01768. Epub 2022 Dec 14. J Med Chem. 2023. PMID: 36517209 Free PMC article.

2

Design, synthesis, evaluation, and crystallographic-based structural studies of HIV-1 protease inhibitors with reduced response to the V82A mutation.

Clemente JC, Robbins A, Graña P, Paleo MR, Correa JF, Villaverde MC, Sardina FJ, Govindasamy L, Agbandje-McKenna M, McKenna R, Dunn BM, Sussman F. Clemente JC, et al. Among authors: paleo mr. J Med Chem. 2008 Feb 28;51(4):852-60. doi: 10.1021/jm701170f. Epub 2008 Jan 24. J Med Chem. 2008. PMID: 18215016

3

Computer-aided structure-based design of multitarget leads for Alzheimer's disease.

Domínguez JL, Fernández-Nieto F, Castro M, Catto M, Paleo MR, Porto S, Sardina FJ, Brea JM, Carotti A, Villaverde MC, Sussman F. Domínguez JL, et al. Among authors: paleo mr. J Chem Inf Model. 2015 Jan 26;55(1):135-48. doi: 10.1021/ci500555g. Epub 2014 Dec 24. J Chem Inf Model. 2015. PMID: 25483751

4

Pharmacological insights emerging from the characterization of a large collection of synthetic cannabinoid receptor agonists designer drugs.

Gioé-Gallo C, Ortigueira S, Brea J, Raïch I, Azuaje J, Paleo MR, Majellaro M, Loza MI, Salas CO, García-Mera X, Navarro G, Sotelo E. Gioé-Gallo C, et al. Among authors: paleo mr. Biomed Pharmacother. 2023 Aug;164:114934. doi: 10.1016/j.biopha.2023.114934. Epub 2023 May 24. Biomed Pharmacother. 2023. PMID: 37236027 Free article.

5

Determination of the effect of cation-pi interactions on the stability of alpha-oxy-organolithium compounds.

Monje P, Paleo MR, García-Río L, Sardina FJ. Monje P, et al. Among authors: paleo mr. J Org Chem. 2008 Sep 19;73(18):7394-7. doi: 10.1021/jo801176d. Epub 2008 Aug 7. J Org Chem. 2008. PMID: 18683984

6

Enantioselective addition of diethylzinc to aldehydes catalyzed by N-(9-phenylfluoren-9-yl) beta-amino alcohols.

Paleo MR, Cabeza I I, Sardina FJ. Paleo MR, et al. J Org Chem. 2000 Apr 7;65(7):2108-13. doi: 10.1021/jo9917083. J Org Chem. 2000. PMID: 10774033

7

Stereoselective Reactions of N-(9-Phenylfluoren-9-yl)-4-oxoproline Enolates. An Expedient Route for the Preparation of Conformationally Restricted Amino Acid Analogues.

Blanco MJ, Paleo MR, Penide C, Sardina FJ. Blanco MJ, et al. Among authors: paleo mr. J Org Chem. 1999 Nov 26;64(24):8786-8793. doi: 10.1021/jo990283h. J Org Chem. 1999. PMID: 11674780

8

Bis-enolates with Extended π-Conjugation Are Powerful Nucleophiles: A Study of Their Alkylation Reactions with Very Hindered C-Electrophiles.

Castroagudín M, Lobato R, Martínez-García L, Sardina FJ, Paleo MR. Castroagudín M, et al. Among authors: paleo mr. J Org Chem. 2019 Dec 20;84(24):15805-15816. doi: 10.1021/acs.joc.9b01961. Epub 2019 Dec 12. J Org Chem. 2019. PMID: 31778066

9

Stereoselective Synthesis of Hydrindane and Hydroazulene Derivatives by Transannular Cyclization of Nine- and Ten-Membered Carbocycles.

Martínez-García L, Prado G, Góñez KV, Paleo MR, Sardina FJ. Martínez-García L, et al. Among authors: paleo mr. J Org Chem. 2021 Oct 1;86(19):13684-13692. doi: 10.1021/acs.joc.1c01751. Epub 2021 Sep 14. J Org Chem. 2021. PMID: 34519499

10

C-C Bond-Forming and Bond-Breaking Processes from the Reaction of Diesters with Me₃SnLi. Synthesis of Complex Bridged Polycycles and Dialkyl Aromatic Compounds.

Martínez-García L, Lobato R, Prado G, Monje P, Sardina FJ, Paleo MR. Martínez-García L, et al. Among authors: paleo mr. J Org Chem. 2019 Feb 15;84(4):1887-1897. doi: 10.1021/acs.joc.8b02891. Epub 2019 Jan 30. J Org Chem. 2019. PMID: 30665302

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