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Intranasal administration of Escherichia coli Nissle expressing the spike protein of SARS-CoV-2 induces long-term immunization and prevents spike protein-mediated lung injury in mice.
Sarnelli G, Del Re A, Palenca I, Franzin SB, Lu J, Seguella L, Zilli A, Pesce M, Rurgo S, Esposito G, Sanseverino W, Esposito G. Sarnelli G, et al. Among authors: palenca i. Biomed Pharmacother. 2024 May;174:116441. doi: 10.1016/j.biopha.2024.116441. Epub 2024 Mar 21. Biomed Pharmacother. 2024. PMID: 38518597 Free article.
Intrarectal Administration of Adelmidrol plus Hyaluronic Acid Gel Ameliorates Experimental Colitis in Mice and Inhibits Pro-Inflammatory Response in Ex Vivo Cultured Biopsies Derived from Ulcerative Colitis-Affected Patients.
Palenca I, Seguella L, Zilli A, Basili Franzin S, Del Re A, Pepi F, Troiani A, Pesce M, Rurgo S, De Palma FDE, Luglio G, Tropeano FP, Sarnelli G, Esposito G. Palenca I, et al. Int J Mol Sci. 2023 Dec 21;25(1):165. doi: 10.3390/ijms25010165. Int J Mol Sci. 2023. PMID: 38203336 Free PMC article.
Miconazole-like Scaffold is a Promising Lead for Naegleria fowleri-Specific CYP51 Inhibitors.
Sharma V, Madia VN, Tudino V, Nguyen JV, Debnath A, Messore A, Ialongo D, Patacchini E, Palenca I, Basili Franzin S, Seguella L, Esposito G, Petrucci R, Di Matteo P, Bortolami M, Saccoliti F, Di Santo R, Scipione L, Costi R, Podust LM. Sharma V, et al. Among authors: palenca i. J Med Chem. 2023 Dec 28;66(24):17059-17073. doi: 10.1021/acs.jmedchem.3c01898. Epub 2023 Dec 12. J Med Chem. 2023. PMID: 38085955 Free PMC article.
Oral Immunization with Escherichia coli Nissle 1917 Expressing SARS-CoV-2 Spike Protein Induces Mucosal and Systemic Antibody Responses in Mice.
Sarnelli G, Del Re A, Pesce M, Lu J, Esposito G, Sanseverino W, Corpetti C, Basili Franzin S, Seguella L, Palenca I, Rurgo S, De Palma FDE, Zilli A, Esposito G. Sarnelli G, et al. Among authors: palenca i. Biomolecules. 2023 Mar 21;13(3):569. doi: 10.3390/biom13030569. Biomolecules. 2023. PMID: 36979504 Free PMC article.
Next-Generation Probiotics for Inflammatory Bowel Disease.
Pesce M, Seguella L, Del Re A, Lu J, Palenca I, Corpetti C, Rurgo S, Sanseverino W, Sarnelli G, Esposito G. Pesce M, et al. Among authors: palenca i. Int J Mol Sci. 2022 May 13;23(10):5466. doi: 10.3390/ijms23105466. Int J Mol Sci. 2022. PMID: 35628274 Free PMC article. Review.
Cannabidiol inhibits SARS-Cov-2 spike (S) protein-induced cytotoxicity and inflammation through a PPARγ-dependent TLR4/NLRP3/Caspase-1 signaling suppression in Caco-2 cell line.
Corpetti C, Del Re A, Seguella L, Palenca I, Rurgo S, De Conno B, Pesce M, Sarnelli G, Esposito G. Corpetti C, et al. Among authors: palenca i. Phytother Res. 2021 Dec;35(12):6893-6903. doi: 10.1002/ptr.7302. Epub 2021 Oct 12. Phytother Res. 2021. PMID: 34643000 Free PMC article.
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