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IVIVE: Facilitating the Use of In Vitro Toxicity Data in Risk Assessment and Decision Making.
Chang X, Tan YM, Allen DG, Bell S, Brown PC, Browning L, Ceger P, Gearhart J, Hakkinen PJ, Kabadi SV, Kleinstreuer NC, Lumen A, Matheson J, Paini A, Pangburn HA, Petersen EJ, Reinke EN, Ribeiro AJS, Sipes N, Sweeney LM, Wambaugh JF, Wange R, Wetmore BA, Mumtaz M. Chang X, et al. Among authors: paini a. Toxics. 2022 May 1;10(5):232. doi: 10.3390/toxics10050232. Toxics. 2022. PMID: 35622645 Free PMC article. Review.
In vitro to in vivo extrapolation for high throughput prioritization and decision making.
Bell SM, Chang X, Wambaugh JF, Allen DG, Bartels M, Brouwer KLR, Casey WM, Choksi N, Ferguson SS, Fraczkiewicz G, Jarabek AM, Ke A, Lumen A, Lynn SG, Paini A, Price PS, Ring C, Simon TW, Sipes NS, Sprankle CS, Strickland J, Troutman J, Wetmore BA, Kleinstreuer NC. Bell SM, et al. Among authors: paini a. Toxicol In Vitro. 2018 Mar;47:213-227. doi: 10.1016/j.tiv.2017.11.016. Epub 2017 Dec 5. Toxicol In Vitro. 2018. PMID: 29203341 Free PMC article. Review.
Aggregate Exposure Pathways in Support of Risk Assessment.
Tan YM, Leonard JA, Edwards S, Teeguarden J, Paini A, Egeghy P. Tan YM, et al. Among authors: paini a. Curr Opin Toxicol. 2018 Jun;9:8-13. doi: 10.1016/j.cotox.2018.03.006. Epub 2018 Mar 29. Curr Opin Toxicol. 2018. PMID: 29736486 Free PMC article.
Pathway-based predictive approaches for non-animal assessment of acute inhalation toxicity.
Clippinger AJ, Allen D, Behrsing H, BéruBé KA, Bolger MB, Casey W, DeLorme M, Gaça M, Gehen SC, Glover K, Hayden P, Hinderliter P, Hotchkiss JA, Iskandar A, Keyser B, Luettich K, Ma-Hock L, Maione AG, Makena P, Melbourne J, Milchak L, Ng SP, Paini A, Page K, Patlewicz G, Prieto P, Raabe H, Reinke EN, Roper C, Rose J, Sharma M, Spoo W, Thorne PS, Wilson DM, Jarabek AM. Clippinger AJ, et al. Among authors: paini a. Toxicol In Vitro. 2018 Oct;52:131-145. doi: 10.1016/j.tiv.2018.06.009. Epub 2018 Jun 20. Toxicol In Vitro. 2018. PMID: 29908304 Free PMC article. Review.
Next generation physiologically based kinetic (NG-PBK) models in support of regulatory decision making.
Paini A, Leonard JA, Joossens E, Bessems JGM, Desalegn A, Dorne JL, Gosling JP, Heringa MB, Klaric M, Kliment T, Kramer NI, Loizou G, Louisse J, Lumen A, Madden JC, Patterson EA, Proença S, Punt A, Setzer RW, Suciu N, Troutman J, Yoon M, Worth A, Tan YM. Paini A, et al. Comput Toxicol. 2019 Feb;9:61-72. doi: 10.1016/j.comtox.2018.11.002. Comput Toxicol. 2019. PMID: 31008414 Free PMC article. Review.
PBPK model reporting template for chemical risk assessment applications.
Tan YM, Chan M, Chukwudebe A, Domoradzki J, Fisher J, Hack CE, Hinderliter P, Hirasawa K, Leonard J, Lumen A, Paini A, Qian H, Ruiz P, Wambaugh J, Zhang F, Embry M. Tan YM, et al. Among authors: paini a. Regul Toxicol Pharmacol. 2020 Aug;115:104691. doi: 10.1016/j.yrtph.2020.104691. Epub 2020 Jun 2. Regul Toxicol Pharmacol. 2020. PMID: 32502513 Free PMC article. Review.
176 results