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Expression of Cyclin E1 in hepatic stellate cells is critical for the induction and progression of liver fibrosis and hepatocellular carcinoma in mice.
Otto J, Verwaayen A, Penners C, Hundertmark J, Lin C, Kallen C, Paffen D, Otto T, Berger H, Tacke F, Weiskirchen R, Nevzorova YA, Bartneck M, Trautwein C, Sonntag R, Liedtke C. Otto J, et al. Among authors: paffen d. Cell Death Dis. 2023 Aug 24;14(8):549. doi: 10.1038/s41419-023-06077-4. Cell Death Dis. 2023. PMID: 37620309 Free PMC article.
Lack of Cyclin E1 in hepatocytes aggravates ethanol-induced liver injury and hepatic steatosis in experimental murine model of acute and chronic alcohol-associated liver disease.
Ramadori P, Woitok MM, Estévez-Vázquez O, Benedé-Ubieto R, Leal-Lassalle H, Lamas-Paz A, Guo F, Fabre J, Otto J, Verwaayen A, Reissing J, Bruns T, Erschfeld S, Haas U, Paffen D, Nelson LJ, Vaquero J, Bañares R, Trautwein C, Cubero FJ, Liedtke C, Nevzorova YA. Ramadori P, et al. Among authors: paffen d. Biochim Biophys Acta Mol Basis Dis. 2023 Apr;1869(4):166646. doi: 10.1016/j.bbadis.2023.166646. Epub 2023 Feb 1. Biochim Biophys Acta Mol Basis Dis. 2023. PMID: 36736843 Free article.