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Coordinated activation of c-Src and FOXM1 drives tumor cell proliferation and breast cancer progression.
Nandi I, Smith HW, Sanguin-Gendreau V, Ji L, Pacis A, Papavasiliou V, Zuo D, Nam S, Attalla SS, Kim SH, Lusson S, Kuasne H, Fortier AM, Savage P, Martinez Ramirez C, Park M, Katzenellenbogen JA, Katzenellenbogen BS, Muller WJ. Nandi I, et al. Among authors: pacis a. J Clin Invest. 2023 Apr 3;133(7):e162324. doi: 10.1172/JCI162324. J Clin Invest. 2023. PMID: 36795481 Free PMC article.
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics.
Piché J, Gosset N, Legault LM, Pacis A, Oneglia A, Caron M, Chetaille P, Barreiro L, Liu D, Qi X, Nattel S, Leclerc S, Breton-Larrivée M; CoHEART Consortium; McGraw S, Andelfinger G. Piché J, et al. Among authors: pacis a. Cell Mol Gastroenterol Hepatol. 2019;7(2):411-431. doi: 10.1016/j.jcmgh.2018.10.011. Epub 2018 Oct 24. Cell Mol Gastroenterol Hepatol. 2019. PMID: 30739867 Free PMC article.
Chemogenomic profiling of breast cancer patient-derived xenografts reveals targetable vulnerabilities for difficult-to-treat tumors.
Savage P, Pacis A, Kuasne H, Liu L, Lai D, Wan A, Dankner M, Martinez C, Muñoz-Ramos V, Pilon V, Monast A, Zhao H, Souleimanova M, Annis MG, Aguilar-Mahecha A, Lafleur J, Bertos NR, Asselah J, Bouganim N, Petrecca K, Siegel PM, Omeroglu A, Shah SP, Aparicio S, Basik M, Meterissian S, Park M. Savage P, et al. Among authors: pacis a. Commun Biol. 2020 Jun 16;3(1):310. doi: 10.1038/s42003-020-1042-x. Commun Biol. 2020. PMID: 32546838 Free PMC article.
Evolution of chromosome-arm aberrations in breast cancer through genetic network rewiring.
Kuzmin E, Baker TM, Lesluyes T, Monlong J, Abe KT, Coelho PP, Schwartz M, Del Corpo J, Zou D, Morin G, Pacis A, Yang Y, Martinez C, Barber J, Kuasne H, Li R, Bourgey M, Fortier AM, Davison PG, Omeroglu A, Guiot MC, Morris Q, Kleinman CL, Huang S, Gingras AC, Ragoussis J, Bourque G, Van Loo P, Park M. Kuzmin E, et al. Among authors: pacis a. Cell Rep. 2024 Apr 23;43(4):113988. doi: 10.1016/j.celrep.2024.113988. Epub 2024 Mar 22. Cell Rep. 2024. PMID: 38517886 Free PMC article.
Alveolar macrophages from persons living with HIV show impaired epigenetic response to Mycobacterium tuberculosis.
Correa-Macedo W, Fava VM, Orlova M, Cassart P, Olivenstein R, Sanz J, Xu YZ, Dumaine A, Sindeaux RH, Yotova V, Pacis A, Girouard J, Kalsdorf B, Lange C, Routy JP, Barreiro LB, Schurr E. Correa-Macedo W, et al. Among authors: pacis a. J Clin Invest. 2021 Nov 15;131(22):e148013. doi: 10.1172/JCI148013. J Clin Invest. 2021. PMID: 34473646 Free PMC article.
ADRA1A-Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP.
Rahbani JF, Scholtes C, Lagarde DM, Hussain MF, Roesler A, Dykstra CB, Bunk J, Samborska B, O'Brien SL, Tripp E, Pacis A, Angueira AR, Johansen OS, Cinkornpumin J, Hossain I, Lynes MD, Zhang Y, White AP, Pastor WA, Chondronikola M, Sidossis L, Klein S, Kralli A, Cypess AM, Pedersen SB, Jessen N, Tseng YH, Gerhart-Hines Z, Seale P, Calebiro D, Giguère V, Kazak L. Rahbani JF, et al. Among authors: pacis a. Nat Metab. 2022 Nov;4(11):1459-1473. doi: 10.1038/s42255-022-00667-w. Epub 2022 Nov 7. Nat Metab. 2022. PMID: 36344764 Free PMC article.
Chemokine expression predicts T cell-inflammation and improved survival with checkpoint inhibition across solid cancers.
Romero JM, Titmuss E, Wang Y, Vafiadis J, Pacis A, Jang GH, Zhang A, Golesworthy B, Lenko T, Williamson LM, Grünwald B, O'Kane GM, Jones SJM, Marra MA, Wilson JM, Gallinger S, Laskin J, Zogopoulos G. Romero JM, et al. Among authors: pacis a. NPJ Precis Oncol. 2023 Aug 9;7(1):73. doi: 10.1038/s41698-023-00428-2. NPJ Precis Oncol. 2023. PMID: 37558751 Free PMC article.
37 results