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Cytochromes P450 catalyze the reduction of α,β-unsaturated aldehydes.
Amunom I, Dieter LJ, Tamasi V, Cai J, Conklin DJ, Srivastava S, Martin MV, Guengerich FP, Prough RA. Amunom I, et al. Chem Res Toxicol. 2011 Aug 15;24(8):1223-30. doi: 10.1021/tx200080b. Epub 2011 Jul 29. Chem Res Toxicol. 2011. PMID: 21766881 Free PMC article.
Aldehyde reduction by cytochrome P450.
Amunom I, Srivastava S, Prough RA. Amunom I, et al. Curr Protoc Toxicol. 2011 May;Chapter 4:Unit4.37. doi: 10.1002/0471140856.tx0437s48. Curr Protoc Toxicol. 2011. PMID: 21553396 Free PMC article.
Oral exposure to acrolein exacerbates atherosclerosis in apoE-null mice.
Srivastava S, Sithu SD, Vladykovskaya E, Haberzettl P, Hoetker DJ, Siddiqui MA, Conklin DJ, D'Souza SE, Bhatnagar A. Srivastava S, et al. Atherosclerosis. 2011 Apr;215(2):301-8. doi: 10.1016/j.atherosclerosis.2011.01.001. Epub 2011 Mar 2. Atherosclerosis. 2011. PMID: 21371710 Free PMC article.
Aldose reductase decreases endoplasmic reticulum stress in ischemic hearts.
Keith RJ, Haberzettl P, Vladykovskaya E, Hill BG, Kaiserova K, Srivastava S, Barski O, Bhatnagar A. Keith RJ, et al. Chem Biol Interact. 2009 Mar 16;178(1-3):242-9. doi: 10.1016/j.cbi.2008.10.055. Epub 2008 Nov 11. Chem Biol Interact. 2009. PMID: 19041636 Free PMC article.