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Year Number of Results
2020 2
2021 13
2022 10
2023 9
2024 4

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36 results

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Page 1
MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis.
Cho MG, Kumar RJ, Lin CC, Boyer JA, Shahir JA, Fagan-Solis K, Simpson DA, Fan C, Foster CE, Goddard AM, Lerner LM, Ellington SW, Wang Q, Wang Y, Ho AY, Liu P, Perou CM, Zhang Q, McGinty RK, Purvis JE, Gupta GP. Cho MG, et al. Nature. 2024 Jan;625(7995):585-592. doi: 10.1038/s41586-023-06889-6. Epub 2024 Jan 10. Nature. 2024. PMID: 38200309 Free PMC article.
Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities.
Krais JJ, Glass DJ, Chudoba I, Wang Y, Feng W, Simpson D, Patel P, Liu Z, Neumann-Domer R, Betsch RG, Bernhardy AJ, Bradbury AM, Conger J, Yueh WT, Nacson J, Pomerantz RT, Gupta GP, Testa JR, Johnson N. Krais JJ, et al. Nat Commun. 2023 Nov 24;14(1):7714. doi: 10.1038/s41467-023-43446-1. Nat Commun. 2023. PMID: 38001070 Free PMC article.
Stepwise requirements for polymerases δ and θ in theta-mediated end joining.
Stroik S, Carvajal-Garcia J, Gupta D, Edwards A, Luthman A, Wyatt DW, Dannenberg RL, Feng W, Kunkel TA, Gupta GP, Hedglin M, Wood R, Doublié S, Rothenberg E, Ramsden DA. Stroik S, et al. Nature. 2023 Nov;623(7988):836-841. doi: 10.1038/s41586-023-06729-7. Epub 2023 Nov 15. Nature. 2023. PMID: 37968395
Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction.
Kefala Stavridi A, Gontier A, Morin V, Frit P, Ropars V, Barboule N, Racca C, Jonchhe S, Morten MJ, Andreani J, Rak A, Legrand P, Bourand-Plantefol A, Hardwick SW, Chirgadze DY, Davey P, De Oliveira TM, Rothenberg E, Britton S, Calsou P, Blundell TL, Varela PF, Chaplin AK, Charbonnier JB. Kefala Stavridi A, et al. Nucleic Acids Res. 2023 Nov 27;51(21):11732-11747. doi: 10.1093/nar/gkad863. Nucleic Acids Res. 2023. PMID: 37870477 Free PMC article.
ORC1 binds to cis-transcribed RNAs for efficient activation of replication origins.
Mas AM, Goñi E, Ruiz de Los Mozos I, Arcas A, Statello L, González J, Blázquez L, Lee WTC, Gupta D, Sejas Á, Hoshina S, Armaos A, Tartaglia GG, Waga S, Ule J, Rothenberg E, Gómez M, Huarte M. Mas AM, et al. Nat Commun. 2023 Jul 24;14(1):4447. doi: 10.1038/s41467-023-40105-3. Nat Commun. 2023. PMID: 37488096 Free PMC article.
Templated insertions-DNA repair gets acrobatic.
Stroik S, Luthman AJ, Ramsden DA. Stroik S, et al. Environ Mol Mutagen. 2024 Apr;65 Suppl 1(Suppl 1):82-89. doi: 10.1002/em.22564. Epub 2023 Jul 28. Environ Mol Mutagen. 2024. PMID: 37438951 Review.
36 results