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Small molecule DnaK modulators targeting the beta-domain.
Cellitti J, Zhang Z, Wang S, Wu B, Yuan H, Hasegawa P, Guiney DG, Pellecchia M. Cellitti J, et al. Chem Biol Drug Des. 2009 Oct;74(4):349-57. doi: 10.1111/j.1747-0285.2009.00869.x. Epub 2009 Aug 20. Chem Biol Drug Des. 2009. PMID: 19694756 Free PMC article.
Perspectives on NMR in drug discovery: a technique comes of age.
Pellecchia M, Bertini I, Cowburn D, Dalvit C, Giralt E, Jahnke W, James TL, Homans SW, Kessler H, Luchinat C, Meyer B, Oschkinat H, Peng J, Schwalbe H, Siegal G. Pellecchia M, et al. Nat Rev Drug Discov. 2008 Sep;7(9):738-45. doi: 10.1038/nrd2606. Nat Rev Drug Discov. 2008. PMID: 19172689 Free PMC article. Review.