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Lights and shadows in the challenge of binding acyclovir, a synthetic purine-like nucleoside with antiviral activity, at an apical-distal coordination site in copper(II)-polyamine chelates.
Pérez-Toro I, Domínguez-Martín A, Choquesillo-Lazarte D, Vílchez-Rodríguez E, González-Pérez JM, Castiñeiras A, Niclós-Gutiérrez J. Pérez-Toro I, et al. J Inorg Biochem. 2015 Jul;148:84-92. doi: 10.1016/j.jinorgbio.2015.03.006. Epub 2015 Mar 23. J Inorg Biochem. 2015. PMID: 25863571
Structural insights on the molecular recognition patterns between N(6)-substituted adenines and N-(aryl-methyl)iminodiacetate copper(II) chelates.
Domínguez-Martín A, García-Raso A, Cabot C, Choquesillo-Lazarte D, Pérez-Toro I, Matilla-Hernández A, Castiñeiras A, Niclós-Gutiérrez J. Domínguez-Martín A, et al. Among authors: perez toro i. J Inorg Biochem. 2013 Oct;127:141-9. doi: 10.1016/j.jinorgbio.2013.02.002. Epub 2013 Feb 15. J Inorg Biochem. 2013. PMID: 23490423
Molecular recognition between adenine or 2,6-diaminopurine and copper(II) chelates with N,O2,S-tripodal tetradentate chelators having thioether or disulfide donor groups.
González-Pérez JM, Choquesillo-Lazarte D, Domínguez-Martín A, El Bakkali H, García-Rubiño ME, Pérez-Toro I, Vílchez-Rodríguez E, Castiñeiras A, Nurchi VM, Niclós-Gutiérrez J. González-Pérez JM, et al. Among authors: perez toro i. J Inorg Biochem. 2015 Oct;151:75-86. doi: 10.1016/j.jinorgbio.2015.05.014. Epub 2015 Jun 3. J Inorg Biochem. 2015. PMID: 26190672
Complex formation equilibria of polyamine ligands with copper(II) and zinc(II).
Nurchi VM, Crisponi G, Sanna G, Pérez-Toro I, Niclos-Gutierrez J, Gonzalez-Perez MJ, Domínguez Martín A. Nurchi VM, et al. Among authors: perez toro i. J Inorg Biochem. 2019 May;194:26-33. doi: 10.1016/j.jinorgbio.2019.02.006. Epub 2019 Feb 18. J Inorg Biochem. 2019. PMID: 30807891