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Monocarboxylate transporters in the brain and in cancer.
Pérez-Escuredo J, Van Hée VF, Sboarina M, Falces J, Payen VL, Pellerin L, Sonveaux P. Pérez-Escuredo J, et al. Biochim Biophys Acta. 2016 Oct;1863(10):2481-97. doi: 10.1016/j.bbamcr.2016.03.013. Epub 2016 Mar 16. Biochim Biophys Acta. 2016. PMID: 26993058 Free PMC article. Review.
Lactate does not activate NF-κB in oxidative tumor cells.
Van Hée VF, Pérez-Escuredo J, Cacace A, Copetti T, Sonveaux P. Van Hée VF, et al. Front Pharmacol. 2015 Oct 13;6:228. doi: 10.3389/fphar.2015.00228. eCollection 2015. Front Pharmacol. 2015. PMID: 26528183 Free PMC article.
Lactate promotes glutamine uptake and metabolism in oxidative cancer cells.
Pérez-Escuredo J, Dadhich RK, Dhup S, Cacace A, Van Hée VF, De Saedeleer CJ, Sboarina M, Rodriguez F, Fontenille MJ, Brisson L, Porporato PE, Sonveaux P. Pérez-Escuredo J, et al. Cell Cycle. 2016;15(1):72-83. doi: 10.1080/15384101.2015.1120930. Cell Cycle. 2016. PMID: 26636483 Free PMC article.
A mitochondrial switch promotes tumor metastasis.
Porporato PE, Payen VL, Pérez-Escuredo J, De Saedeleer CJ, Danhier P, Copetti T, Dhup S, Tardy M, Vazeille T, Bouzin C, Feron O, Michiels C, Gallez B, Sonveaux P. Porporato PE, et al. Cell Rep. 2014 Aug 7;8(3):754-66. doi: 10.1016/j.celrep.2014.06.043. Epub 2014 Jul 24. Cell Rep. 2014. PMID: 25066121 Free article.
Inhibition of FLT3 and PIM Kinases by EC-70124 Exerts Potent Activity in Preclinical Models of Acute Myeloid Leukemia.
Puente-Moncada N, Costales P, Antolín I, Núñez LE, Oro P, Hermosilla MA, Pérez-Escuredo J, Ríos-Lombardía N, Sanchez-Sanchez AM, Luño E, Rodríguez C, Martín V, Morís F. Puente-Moncada N, et al. Among authors: perez escuredo j. Mol Cancer Ther. 2018 Mar;17(3):614-624. doi: 10.1158/1535-7163.MCT-17-0530. Epub 2018 Jan 16. Mol Cancer Ther. 2018. PMID: 29339551
The multikinase inhibitor EC-70124 synergistically increased the antitumor activity of doxorubicin in sarcomas.
Estupiñan O, Santos L, Rodriguez A, Fernandez-Nevado L, Costales P, Perez-Escuredo J, Hermosilla MA, Oro P, Rey V, Tornin J, Allonca E, Fernandez-Garcia MT, Alvarez-Fernandez C, Braña A, Astudillo A, Menendez ST, Moris F, Rodriguez R. Estupiñan O, et al. Among authors: perez escuredo j. Int J Cancer. 2019 Jul 1;145(1):254-266. doi: 10.1002/ijc.32081. Epub 2019 Jan 14. Int J Cancer. 2019. PMID: 30575954 Free article.
KRAS and BRAF mutations in sinonasal cancer.
López F, García Inclán C, Pérez-Escuredo J, Alvarez Marcos C, Scola B, Suárez C, Llorente JL, Hermsen MA. López F, et al. Oral Oncol. 2012 Aug;48(8):692-7. doi: 10.1016/j.oraloncology.2012.02.018. Epub 2012 Mar 27. Oral Oncol. 2012. PMID: 22459936
The Mithralog EC-7072 Induces Chronic Lymphocytic Leukemia Cell Death by Targeting Tonic B-Cell Receptor Signaling.
Lorenzo-Herrero S, Sordo-Bahamonde C, Bretones G, Payer ÁR, González-Rodríguez AP, González-García E, Pérez-Escuredo J, Villa-Álvarez M, Núñez LE, Morís F, Gonzalez S, López-Soto A. Lorenzo-Herrero S, et al. Among authors: perez escuredo j. Front Immunol. 2019 Oct 18;10:2455. doi: 10.3389/fimmu.2019.02455. eCollection 2019. Front Immunol. 2019. PMID: 31681329 Free PMC article.
29 results