Owen A - Search Results

1

Unlike Chloroquine, Mefloquine Inhibits SARS-CoV-2 Infection in Physiologically Relevant Cells.

Sacramento CQ, Fintelman-Rodrigues N, Dias SSG, Temerozo JR, Da Silva APD, da Silva CS, Blanco C, Ferreira AC, Mattos M, Soares VC, Pereira-Dutra F, Miranda MD, Barreto-Vieira DF, da Silva MAN, Santos SS, Torres M, Chaves OA, Rajoli RKR, Paccanaro A, Owen A, Bou-Habib DC, Bozza PT, Souza TML. Sacramento CQ, et al. Among authors: owen a. Viruses. 2022 Feb 11;14(2):374. doi: 10.3390/v14020374. Viruses. 2022. PMID: 35215969 Free PMC article.

2

Physiologically Based Pharmacokinetic Modelling to Inform Development of Intramuscular Long-Acting Nanoformulations for HIV.

Rajoli RK, Back DJ, Rannard S, Freel Meyers CL, Flexner C, Owen A, Siccardi M. Rajoli RK, et al. Among authors: owen a. Clin Pharmacokinet. 2015 Jun;54(6):639-50. doi: 10.1007/s40262-014-0227-1. Clin Pharmacokinet. 2015. PMID: 25523214 Free PMC article.

3

Efavirenz Is Predicted To Accumulate in Brain Tissue: an In Silico, In Vitro, and In Vivo Investigation.

Curley P, Rajoli RK, Moss DM, Liptrott NJ, Letendre S, Owen A, Siccardi M. Curley P, et al. Among authors: owen a. Antimicrob Agents Chemother. 2016 Dec 27;61(1):e01841-16. doi: 10.1128/AAC.01841-16. Print 2017 Jan. Antimicrob Agents Chemother. 2016. PMID: 27799216 Free PMC article.

4

Use of a physiologically based pharmacokinetic model to simulate drug-drug interactions between antineoplastic and antiretroviral drugs.

Moltó J, Rajoli R, Back D, Valle M, Miranda C, Owen A, Clotet B, Siccardi M. Moltó J, et al. Among authors: owen a. J Antimicrob Chemother. 2017 Mar 1;72(3):805-811. doi: 10.1093/jac/dkw485. J Antimicrob Chemother. 2017. PMID: 27999009

5

In Silico Dose Prediction for Long-Acting Rilpivirine and Cabotegravir Administration to Children and Adolescents.

Rajoli RKR, Back DJ, Rannard S, Meyers CF, Flexner C, Owen A, Siccardi M. Rajoli RKR, et al. Among authors: owen a. Clin Pharmacokinet. 2018 Feb;57(2):255-266. doi: 10.1007/s40262-017-0557-x. Clin Pharmacokinet. 2018. PMID: 28540638 Free PMC article.

6

Physiologically based pharmacokinetic modelling prediction of the effects of dose adjustment in drug-drug interactions between levonorgestrel contraceptive implants and efavirenz-based ART.

Roberts O, Rajoli RKR, Back DJ, Owen A, Darin KM, Fletcher CV, Lamorde M, Scarsi KK, Siccardi M. Roberts O, et al. Among authors: owen a. J Antimicrob Chemother. 2018 Apr 1;73(4):1004-1012. doi: 10.1093/jac/dkx515. J Antimicrob Chemother. 2018. PMID: 29365101 Free PMC article.

7

Derivation of CYP3A4 and CYP2B6 degradation rate constants in primary human hepatocytes: A siRNA-silencing-based approach.

Chan CYS, Roberts O, Rajoli RKR, Liptrott NJ, Siccardi M, Almond L, Owen A. Chan CYS, et al. Among authors: owen a. Drug Metab Pharmacokinet. 2018 Aug;33(4):179-187. doi: 10.1016/j.dmpk.2018.01.004. Epub 2018 Mar 16. Drug Metab Pharmacokinet. 2018. PMID: 29921509 Free article.

8

Modelling the long-acting administration of anti-tuberculosis agents using PBPK: a proof of concept study.

Rajoli RKR, Podany AT, Moss DM, Swindells S, Flexner C, Owen A, Siccardi M. Rajoli RKR, et al. Among authors: owen a. Int J Tuberc Lung Dis. 2018 Aug 1;22(8):937-944. doi: 10.5588/ijtld.17.0515. Int J Tuberc Lung Dis. 2018. PMID: 29991405 Free PMC article.

9

Predicting Drug-Drug Interactions Between Rifampicin and Long-Acting Cabotegravir and Rilpivirine Using Physiologically Based Pharmacokinetic Modeling.

Rajoli RKR, Curley P, Chiong J, Back D, Flexner C, Owen A, Siccardi M. Rajoli RKR, et al. Among authors: owen a. J Infect Dis. 2019 May 5;219(11):1735-1742. doi: 10.1093/infdis/jiy726. J Infect Dis. 2019. PMID: 30566691 Free PMC article.

10

Using mechanistic physiologically-based pharmacokinetic models to assess prenatal drug exposure: Thalidomide versus efavirenz as case studies.

Atoyebi SA, Rajoli RKR, Adejuyigbe E, Owen A, Bolaji O, Siccardi M, Olagunju A. Atoyebi SA, et al. Among authors: owen a. Eur J Pharm Sci. 2019 Dec 1;140:105068. doi: 10.1016/j.ejps.2019.105068. Epub 2019 Sep 10. Eur J Pharm Sci. 2019. PMID: 31518681 Free PMC article.

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