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Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies.
Vicente Miranda H, Szego ÉM, Oliveira LMA, Breda C, Darendelioglu E, de Oliveira RM, Ferreira DG, Gomes MA, Rott R, Oliveira M, Munari F, Enguita FJ, Simões T, Rodrigues EF, Heinrich M, Martins IC, Zamolo I, Riess O, Cordeiro C, Ponces-Freire A, Lashuel HA, Santos NC, Lopes LV, Xiang W, Jovin TM, Penque D, Engelender S, Zweckstetter M, Klucken J, Giorgini F, Quintas A, Outeiro TF. Vicente Miranda H, et al. Among authors: outeiro tf. Brain. 2017 May 1;140(5):1399-1419. doi: 10.1093/brain/awx056. Brain. 2017. PMID: 28398476
Seeding variability of different alpha synuclein strains in synucleinopathies.
Candelise N, Schmitz M, Llorens F, Villar-Piqué A, Cramm M, Thom T, da Silva Correia SM, da Cunha JEG, Möbius W, Outeiro TF, Álvarez VG, Banchelli M, D'Andrea C, de Angelis M, Zafar S, Rabano A, Matteini P, Zerr I. Candelise N, et al. Among authors: outeiro tf. Ann Neurol. 2019 May;85(5):691-703. doi: 10.1002/ana.25446. Epub 2019 Mar 27. Ann Neurol. 2019. PMID: 30805957
Cellular models of alpha-synuclein toxicity and aggregation.
Delenclos M, Burgess JD, Lamprokostopoulou A, Outeiro TF, Vekrellis K, McLean PJ. Delenclos M, et al. Among authors: outeiro tf. J Neurochem. 2019 Sep;150(5):566-576. doi: 10.1111/jnc.14806. Epub 2019 Jul 30. J Neurochem. 2019. PMID: 31265132 Free PMC article. Review.
Molecular characterization of an aggregation-prone variant of alpha-synuclein used to model synucleinopathies.
Masaracchia C, König A, Valiente-Gabioud AA, Peralta P, Favretto F, Strohäker T, Lázaro DF, Zweckstetter M, Fernandez CO, Outeiro TF. Masaracchia C, et al. Among authors: outeiro tf. Biochim Biophys Acta Proteins Proteom. 2020 Jan;1868(1):140298. doi: 10.1016/j.bbapap.2019.140298. Epub 2019 Oct 30. Biochim Biophys Acta Proteins Proteom. 2020. PMID: 31676453
Synucleinopathies: Where we are and where we need to go.
Brás IC, Dominguez-Meijide A, Gerhardt E, Koss D, Lázaro DF, Santos PI, Vasili E, Xylaki M, Outeiro TF. Brás IC, et al. Among authors: outeiro tf. J Neurochem. 2020 May;153(4):433-454. doi: 10.1111/jnc.14965. Epub 2020 Feb 19. J Neurochem. 2020. PMID: 31957016 Free article. Review.
323 results