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Mutations in PCSK9 cause autosomal dominant hypercholesterolemia.
Abifadel M, Varret M, Rabès JP, Allard D, Ouguerram K, Devillers M, Cruaud C, Benjannet S, Wickham L, Erlich D, Derré A, Villéger L, Farnier M, Beucler I, Bruckert E, Chambaz J, Chanu B, Lecerf JM, Luc G, Moulin P, Weissenbach J, Prat A, Krempf M, Junien C, Seidah NG, Boileau C. Abifadel M, et al. Among authors: ouguerram k. Nat Genet. 2003 Jun;34(2):154-6. doi: 10.1038/ng1161. Nat Genet. 2003. PMID: 12730697
Description of a large family with autosomal dominant hypercholesterolemia associated with the APOE p.Leu167del mutation.
Marduel M, Ouguerram K, Serre V, Bonnefont-Rousselot D, Marques-Pinheiro A, Erik Berge K, Devillers M, Luc G, Lecerf JM, Tosolini L, Erlich D, Peloso GM, Stitziel N, Nitchké P, Jaïs JP; French Research Network on ADH; Abifadel M, Kathiresan S, Leren TP, Rabès JP, Boileau C, Varret M. Marduel M, et al. Among authors: ouguerram k. Hum Mutat. 2013 Jan;34(1):83-7. doi: 10.1002/humu.22215. Epub 2012 Oct 11. Hum Mutat. 2013. PMID: 22949395 Free PMC article.
PCSK9 dominant negative mutant results in increased LDL catabolic rate and familial hypobetalipoproteinemia.
Cariou B, Ouguerram K, Zaïr Y, Guerois R, Langhi C, Kourimate S, Benoit I, Le May C, Gayet C, Belabbas K, Dufernez F, Chétiveaux M, Tarugi P, Krempf M, Benlian P, Costet P. Cariou B, et al. Among authors: ouguerram k. Arterioscler Thromb Vasc Biol. 2009 Dec;29(12):2191-7. doi: 10.1161/ATVBAHA.109.194191. Epub 2009 Sep 17. Arterioscler Thromb Vasc Biol. 2009. PMID: 19762784
Plasma PCSK9 measurement by liquid chromatography-Tandem mass spectrometry and comparison with conventional ELISA.
Croyal M, Fall F, Krempf M, Thédrez A, Ouguerram K, Ferchaud-Roucher V, Aguesse A, Billon-Crossouard S, Mata P, Alonso R, Lambert G, Nobécourt E. Croyal M, et al. Among authors: ouguerram k. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Feb 15;1044-1045:24-29. doi: 10.1016/j.jchromb.2016.12.040. Epub 2016 Dec 31. J Chromatogr B Analyt Technol Biomed Life Sci. 2017. PMID: 28064066
Lipoproteins abnormalities in obese insulin-resistant dogs.
Bailhache E, Nguyen P, Krempf M, Siliart B, Magot T, Ouguerram K. Bailhache E, et al. Among authors: ouguerram k. Metabolism. 2003 May;52(5):559-64. doi: 10.1053/meta.2003.50110. Metabolism. 2003. PMID: 12759884
97 results