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Time-resolved FRET strategy to screen GPCR ligand library.
Oueslati N, Hounsou C, Belhocine A, Rodriguez T, Dupuis E, Zwier JM, Trinquet E, Pin JP, Durroux T. Oueslati N, et al. Methods Mol Biol. 2015;1272:23-36. doi: 10.1007/978-1-4939-2336-6_2. Methods Mol Biol. 2015. PMID: 25563174
Homogeneous time-resolved fluorescence-based assay to screen for ligands targeting the growth hormone secretagogue receptor type 1a.
Leyris JP, Roux T, Trinquet E, Verdié P, Fehrentz JA, Oueslati N, Douzon S, Bourrier E, Lamarque L, Gagne D, Galleyrand JC, M'kadmi C, Martinez J, Mary S, Banères JL, Marie J. Leyris JP, et al. Among authors: oueslati n. Anal Biochem. 2011 Jan 15;408(2):253-62. doi: 10.1016/j.ab.2010.09.030. Epub 2010 Sep 24. Anal Biochem. 2011. PMID: 20937574
A fluorescent ligand-binding alternative using Tag-lite® technology.
Zwier JM, Roux T, Cottet M, Durroux T, Douzon S, Bdioui S, Gregor N, Bourrier E, Oueslati N, Nicolas L, Tinel N, Boisseau C, Yverneau P, Charrier-Savournin F, Fink M, Trinquet E. Zwier JM, et al. Among authors: oueslati n. J Biomol Screen. 2010 Dec;15(10):1248-59. doi: 10.1177/1087057110384611. Epub 2010 Oct 25. J Biomol Screen. 2010. PMID: 20974902
Increased Potency and Selectivity for Group III Metabotropic Glutamate Receptor Agonists Binding at Dual sites.
Selvam C, Lemasson IA, Brabet I, Oueslati N, Karaman B, Cabaye A, Tora AS, Commare B, Courtiol T, Cesarini S, McCort-Tranchepain I, Rigault D, Mony L, Bessiron T, McLean H, Leroux FR, Colobert F, Daniel H, Goupil-Lamy A, Bertrand HO, Goudet C, Pin JP, Acher FC. Selvam C, et al. Among authors: oueslati n. J Med Chem. 2018 Mar 8;61(5):1969-1989. doi: 10.1021/acs.jmedchem.7b01438. Epub 2018 Feb 14. J Med Chem. 2018. PMID: 29397723
17 results