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PTPN2 Is a Critical Regulator of Ileal Paneth Cell Viability and Function in Mice.
Canale V, Spalinger MR, Alvarez R, Sayoc-Becerra A, Sanati G, Manz S, Chatterjee P, Santos AN, Lei H, Jahng S, Chu T, Shawki A, Hanson E, Eckmann L, Ouellette AJ, McCole DF. Canale V, et al. Among authors: ouellette aj. Cell Mol Gastroenterol Hepatol. 2023;16(1):39-62. doi: 10.1016/j.jcmgh.2023.03.009. Epub 2023 Apr 7. Cell Mol Gastroenterol Hepatol. 2023. PMID: 37030630 Free PMC article.
Decreased Paneth cell α-defensins promote fibrosis in a choline-deficient L-amino acid-defined high-fat diet-induced mouse model of nonalcoholic steatohepatitis via disrupting intestinal microbiota.
Nakamura S, Nakamura K, Yokoi Y, Shimizu Y, Ohira S, Hagiwara M, Song Z, Gan L, Aizawa T, Hashimoto D, Teshima T, Ouellette AJ, Ayabe T. Nakamura S, et al. Among authors: ouellette aj. Sci Rep. 2023 Mar 9;13(1):3953. doi: 10.1038/s41598-023-30997-y. Sci Rep. 2023. PMID: 36894646 Free PMC article.
Anti-Inflammatory Effects of RTD-1 in a Murine Model of Chronic Pseudomonas aeruginosa Lung Infection: Inhibition of NF-κB, Inflammasome Gene Expression, and Pro-IL-1β Biosynthesis.
Dughbaj MA, Jayne JG, Park AYJ, Bensman TJ, Algorri M, Ouellette AJ, Selsted ME, Beringer PM. Dughbaj MA, et al. Among authors: ouellette aj. Antibiotics (Basel). 2021 Aug 26;10(9):1043. doi: 10.3390/antibiotics10091043. Antibiotics (Basel). 2021. PMID: 34572625 Free PMC article.
RTD-1 therapeutically normalizes synovial gene signatures in rat autoimmune arthritis and suppresses proinflammatory mediators in RA synovial fibroblasts.
Tongaonkar P, Punj V, Subramanian A, Tran DQ, Trinh KK, Schaal JB, Laragione T, Ouellette AJ, Gulko PS, Selsted ME. Tongaonkar P, et al. Among authors: ouellette aj. Physiol Genomics. 2019 Dec 1;51(12):657-667. doi: 10.1152/physiolgenomics.00066.2019. Epub 2019 Nov 25. Physiol Genomics. 2019. PMID: 31762409 Free PMC article.
Essential role of IFN-γ in T cell-associated intestinal inflammation.
Eriguchi Y, Nakamura K, Yokoi Y, Sugimoto R, Takahashi S, Hashimoto D, Teshima T, Ayabe T, Selsted ME, Ouellette AJ. Eriguchi Y, et al. Among authors: ouellette aj. JCI Insight. 2018 Sep 20;3(18):e121886. doi: 10.1172/jci.insight.121886. eCollection 2018 Sep 20. JCI Insight. 2018. PMID: 30232288 Free PMC article.
137 results