Myeloid cells require gp130 signaling for protective anti-inflammatory functions during sepsis.
Sackett SD, Otto T, Mohs A, Sander LE, Strauch S, Streetz KL, Kroy DC, Trautwein C.
Sackett SD, et al. Among authors: otto t.
FASEB J. 2019 May;33(5):6035-6044. doi: 10.1096/fj.201802118R. Epub 2019 Feb 6.
FASEB J. 2019.
PMID: 30726111
Our study highlights the Janus-faced role of IL-6 family cytokines during inflammation, which may explain the failure of IL-6-targeted anti-inflammatory approaches in the treatment of sepsis.-Sackett, S. D., Otto, T., Mohs, A., Sander, L. E., Strauch, S., Streetz, K …
Our study highlights the Janus-faced role of IL-6 family cytokines during inflammation, which may explain the failure of IL-6-targeted anti- …