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Protection of pancreatic islets from oxidative cell death by a peripherally-active morphinan with increased drug safety.
Scholz O, Huß E, Otter S, Herebian D, Hamacher A, Levy LM, Hristeva S, Sanz M, Ajani H, Puentes AR, Hoffmann T, Hogeback J, Unger A, Terheyden S, Reina do Fundo M, Dewidar B, Roden M, Lammert E. Scholz O, et al. Among authors: otter s. Mol Metab. 2023 Sep;75:101775. doi: 10.1016/j.molmet.2023.101775. Epub 2023 Jul 12. Mol Metab. 2023. PMID: 37451343 Free PMC article.
Peripherally active dextromethorphan derivatives lower blood glucose levels by targeting pancreatic islets.
Scholz O, Otter S, Welters A, Wörmeyer L, Dolenšek J, Klemen MS, Pohorec V, Eberhard D, Mrugala J, Hamacher A, Koch A, Sanz M, Hoffmann T, Hogeback J, Herebian D, Klöcker N, Piechot A, Mayatepek E, Meissner T, Stožer A, Lammert E. Scholz O, et al. Among authors: otter s. Cell Chem Biol. 2021 Oct 21;28(10):1474-1488.e7. doi: 10.1016/j.chembiol.2021.05.011. Epub 2021 Jun 11. Cell Chem Biol. 2021. PMID: 34118188 Free article.
Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment.
Marquard J, Otter S, Welters A, Stirban A, Fischer A, Eglinger J, Herebian D, Kletke O, Klemen MS, Stožer A, Wnendt S, Piemonti L, Köhler M, Ferrer J, Thorens B, Schliess F, Rupnik MS, Heise T, Berggren PO, Klöcker N, Meissner T, Mayatepek E, Eberhard D, Kragl M, Lammert E. Marquard J, et al. Among authors: otter s. Nat Med. 2015 Apr;21(4):363-72. doi: 10.1038/nm.3822. Epub 2015 Mar 16. Nat Med. 2015. PMID: 25774850
Effects of dextromethorphan as add-on to sitagliptin on blood glucose and serum insulin concentrations in individuals with type 2 diabetes mellitus: a randomized, placebo-controlled, double-blinded, multiple crossover, single-dose clinical trial.
Marquard J, Stirban A, Schliess F, Sievers F, Welters A, Otter S, Fischer A, Wnendt S, Meissner T, Heise T, Lammert E. Marquard J, et al. Among authors: otter s. Diabetes Obes Metab. 2016 Jan;18(1):100-3. doi: 10.1111/dom.12576. Epub 2015 Oct 26. Diabetes Obes Metab. 2016. PMID: 26362564 Free PMC article. Clinical Trial.
Net survival of men with localized prostate cancer after LDR brachytherapy.
Uribe-Lewis S, Uribe J, Deering C, Langley S, Higgins D, Whiting D, Metawe M, Khaksar S, Mehta S, Mikropoulos C, Otter S, Perna C, Langley S. Uribe-Lewis S, et al. Among authors: otter s. Brachytherapy. 2024 May-Jun;23(3):329-334. doi: 10.1016/j.brachy.2024.02.006. Epub 2024 Mar 26. Brachytherapy. 2024. PMID: 38538414
Multicentre, randomised controlled trial of physiological-based cord clamping versus immediate cord clamping in infants with a congenital diaphragmatic hernia (PinC): statistical analysis plan.
Horn-Oudshoorn EJJ, Vermeulen MJ, Knol R, Bout-Rebel R, Te Pas AB, Hooper SB, Otter SCMC, Wijnen RMH, Crossley KJ, Rafat N, Schaible T, de Boode WP, Debeer A, Urlesberger B, Roberts CT, Kipfmueller F, Capolupo I, Burgos CM, Hansen BE, Reiss IKM, DeKoninck PLJ. Horn-Oudshoorn EJJ, et al. Among authors: otter scmc. Trials. 2024 Mar 20;25(1):198. doi: 10.1186/s13063-024-08027-7. Trials. 2024. PMID: 38509614 Free PMC article. Clinical Trial.
80 results