Ottenhoff THM - Search Results

1

Repurposing Tamoxifen as Potential Host-Directed Therapeutic for Tuberculosis.

Boland R, Heemskerk MT, Forn-Cuní G, Korbee CJ, Walburg KV, Esselink JJ, Carvalho Dos Santos C, de Waal AM, van der Hoeven DCM, van der Sar E, de Ries AS, Xie J, Spaink HP, van der Vaart M, Haks MC, Meijer AH, Ottenhoff THM. Boland R, et al. Among authors: ottenhoff thm. mBio. 2023 Feb 28;14(1):e0302422. doi: 10.1128/mbio.03024-22. Epub 2022 Dec 7. mBio. 2023. PMID: 36475748 Free PMC article.

2

Human anti-inflammatory macrophages induce Foxp3+ GITR+ CD25+ regulatory T cells, which suppress via membrane-bound TGFbeta-1.

Savage ND, de Boer T, Walburg KV, Joosten SA, van Meijgaarden K, Geluk A, Ottenhoff TH. Savage ND, et al. J Immunol. 2008 Aug 1;181(3):2220-6. doi: 10.4049/jimmunol.181.3.2220. J Immunol. 2008. PMID: 18641362

3

Anti-inflammatory M2 type macrophages characterize metastasized and tyrosine kinase inhibitor-treated gastrointestinal stromal tumors.

van Dongen M, Savage ND, Jordanova ES, Briaire-de Bruijn IH, Walburg KV, Ottenhoff TH, Hogendoorn PC, van der Burg SH, Gelderblom H, van Hall T. van Dongen M, et al. Int J Cancer. 2010 Aug 15;127(4):899-909. doi: 10.1002/ijc.25113. Int J Cancer. 2010. PMID: 20013807 Free article.

4

A high-throughput screen for tuberculosis progression.

Carvalho R, de Sonneville J, Stockhammer OW, Savage ND, Veneman WJ, Ottenhoff TH, Dirks RP, Meijer AH, Spaink HP. Carvalho R, et al. PLoS One. 2011 Feb 16;6(2):e16779. doi: 10.1371/journal.pone.0016779. PLoS One. 2011. PMID: 21390204 Free PMC article.

5

Identification of biomarkers for tuberculosis disease using a novel dual-color RT-MLPA assay.

Joosten SA, Goeman JJ, Sutherland JS, Opmeer L, de Boer KG, Jacobsen M, Kaufmann SH, Finos L, Magis-Escurra C, Ota MO, Ottenhoff TH, Haks MC. Joosten SA, et al. Genes Immun. 2012 Jan;13(1):71-82. doi: 10.1038/gene.2011.64. Epub 2011 Sep 29. Genes Immun. 2012. PMID: 21956656

6

Longitudinal immune responses and gene expression profiles in type 1 leprosy reactions.

Geluk A, van Meijgaarden KE, Wilson L, Bobosha K, van der Ploeg-van Schip JJ, van den Eeden SJ, Quinten E, Dijkman K, Franken KL, Haisma EM, Haks MC, van Hees CL, Ottenhoff TH. Geluk A, et al. J Clin Immunol. 2014 Feb;34(2):245-55. doi: 10.1007/s10875-013-9979-x. Epub 2013 Dec 27. J Clin Immunol. 2014. PMID: 24370984

7

The DNA damage-regulated autophagy modulator DRAM1 links mycobacterial recognition via TLR-MYD88 to autophagic defense [corrected].

van der Vaart M, Korbee CJ, Lamers GE, Tengeler AC, Hosseini R, Haks MC, Ottenhoff TH, Spaink HP, Meijer AH. van der Vaart M, et al. Cell Host Microbe. 2014 Jun 11;15(6):753-67. doi: 10.1016/j.chom.2014.05.005. Cell Host Microbe. 2014. PMID: 24922577 Free article.

8

Short-term high-fat diet increases macrophage markers in skeletal muscle accompanied by impaired insulin signalling in healthy male subjects.

Boon MR, Bakker LE, Haks MC, Quinten E, Schaart G, Van Beek L, Wang Y, Van Schinkel L, Van Harmelen V, Meinders AE, Ottenhoff TH, Van Dijk KW, Guigas B, Jazet IM, Rensen PC. Boon MR, et al. Clin Sci (Lond). 2015 Jan;128(2):143-51. doi: 10.1042/CS20140179. Clin Sci (Lond). 2015. PMID: 25148551

9

Clinical immunology and multiplex biomarkers of human tuberculosis.

Walzl G, Haks MC, Joosten SA, Kleynhans L, Ronacher K, Ottenhoff TH. Walzl G, et al. Cold Spring Harb Perspect Med. 2014 Dec 4;5(4):a018515. doi: 10.1101/cshperspect.a018515. Cold Spring Harb Perspect Med. 2014. PMID: 25475107 Free PMC article. Review.

10

Human CD8+ T-cells recognizing peptides from Mycobacterium tuberculosis (Mtb) presented by HLA-E have an unorthodox Th2-like, multifunctional, Mtb inhibitory phenotype and represent a novel human T-cell subset.

van Meijgaarden KE, Haks MC, Caccamo N, Dieli F, Ottenhoff TH, Joosten SA. van Meijgaarden KE, et al. PLoS Pathog. 2015 Mar 24;11(3):e1004671. doi: 10.1371/journal.ppat.1004671. eCollection 2015 Mar. PLoS Pathog. 2015. PMID: 25803478 Free PMC article. Clinical Trial.

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