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Epigenetic upregulation of Schlafen11 renders 
WNT- and SHH-activated medulloblastomas sensitive to cisplatin.
Nakata S, Murai J, Okada M, Takahashi H, Findlay TH, Malebranche K, Parthasarathy A, Miyashita S, Gabdulkhaev R, Benkimoun I, Druillennec S, Chabi S, Hawkins E, Miyahara H, Tateishi K, Yamashita S, Yamada S, Saito T, On J, Watanabe J, Tsukamoto Y, Yoshimura J, Oishi M, Nakano T, Imamura M, Imai C, Yamamoto T, Takeshima H, Sasaki AT, Rodriguez FJ, Nobusawa S, Varlet P, Pouponnot C, Osuka S, Pommier Y, Kakita A, Fujii Y, Raabe EH, Eberhart CG, Natsumeda M. Nakata S, et al. Among authors: osuka s. Neuro Oncol. 2023 May 4;25(5):899-912. doi: 10.1093/neuonc/noac243. Neuro Oncol. 2023. PMID: 36273330 Free PMC article.
Arylsulfonamide 64B Inhibits Hypoxia/HIF-Induced Expression of c-Met and CXCR4 and Reduces Primary Tumor Growth and Metastasis of Uveal Melanoma.
Dong L, You S, Zhang Q, Osuka S, Devi NS, Kaluz S, Ferguson JH, Yang H, Chen G, Wang B, Grossniklaus HE, Van Meir EG. Dong L, et al. Among authors: osuka s. Clin Cancer Res. 2019 Apr 1;25(7):2206-2218. doi: 10.1158/1078-0432.CCR-18-1368. Epub 2018 Dec 18. Clin Cancer Res. 2019. PMID: 30563937 Free PMC article.
IGF2 preserves osteosarcoma cell survival by creating an autophagic state of dormancy that protects cells against chemotherapeutic stress.
Shimizu T, Sugihara E, Yamaguchi-Iwai S, Tamaki S, Koyama Y, Kamel W, Ueki A, Ishikawa T, Chiyoda T, Osuka S, Onishi N, Ikeda H, Kamei J, Matsuo K, Fukuchi Y, Nagai T, Toguchida J, Toyama Y, Muto A, Saya H. Shimizu T, et al. Among authors: osuka s. Cancer Res. 2014 Nov 15;74(22):6531-41. doi: 10.1158/0008-5472.CAN-14-0914. Epub 2014 Oct 1. Cancer Res. 2014. PMID: 25273088
126 results