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Page 1
Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity.
Ostkamp P, Salmen A, Pignolet B, Görlich D, Andlauer TFM, Schulte-Mecklenbeck A, Gonzalez-Escamilla G, Bucciarelli F, Gennero I, Breuer J, Antony G, Schneider-Hohendorf T, Mykicki N, Bayas A, Then Bergh F, Bittner S, Hartung HP, Friese MA, Linker RA, Luessi F, Lehmann-Horn K, Mühlau M, Paul F, Stangel M, Tackenberg B, Tumani H, Warnke C, Weber F, Wildemann B, Zettl UK, Ziemann U, Müller-Myhsok B, Kümpfel T, Klotz L, Meuth SG, Zipp F, Hemmer B, Hohlfeld R, Brassat D, Gold R, Gross CC, Lukas C, Groppa S, Loser K, Wiendl H, Schwab N; German Competence Network Multiple Sclerosis (KKNMS) and the BIONAT Network. Ostkamp P, et al. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2018457118. doi: 10.1073/pnas.2018457118. Proc Natl Acad Sci U S A. 2021. PMID: 33376202 Free PMC article.
High anti-JCPyV serum titers coincide with high CSF cell counts in RRMS patients.
Schneider-Hohendorf T, Schulte-Mecklenbeck A, Ostkamp P, Janoschka C, Pawlitzki M, Luessi F, Zipp F, Meuth SG, Klotz L, Wiendl H, Gross CC, Schwab N. Schneider-Hohendorf T, et al. Among authors: ostkamp p. Mult Scler. 2021 Sep;27(10):1491-1496. doi: 10.1177/1352458520970103. Epub 2020 Nov 5. Mult Scler. 2021. PMID: 33150829 Free PMC article.
VLA-2 blockade in vivo by vatelizumab induces CD4+FoxP3+ regulatory T cells.
Breuer J, Schneider-Hohendorf T, Ostkamp P, Herich S, Rakhade S, Antonijevic I, Klotz L, Wiendl H, Schwab N. Breuer J, et al. Among authors: ostkamp p. Int Immunol. 2019 May 21;31(6):407-412. doi: 10.1093/intimm/dxz018. Int Immunol. 2019. PMID: 30783682 Clinical Trial.
Broader Epstein-Barr virus-specific T cell receptor repertoire in patients with multiple sclerosis.
Schneider-Hohendorf T, Gerdes LA, Pignolet B, Gittelman R, Ostkamp P, Rubelt F, Raposo C, Tackenberg B, Riepenhausen M, Janoschka C, Wünsch C, Bucciarelli F, Flierl-Hecht A, Beltrán E, Kümpfel T, Anslinger K, Gross CC, Chapman H, Kaplan I, Brassat D, Wekerle H, Kerschensteiner M, Klotz L, Lünemann JD, Hohlfeld R, Liblau R, Wiendl H, Schwab N. Schneider-Hohendorf T, et al. Among authors: ostkamp p. J Exp Med. 2022 Nov 7;219(11):e20220650. doi: 10.1084/jem.20220650. Epub 2022 Sep 1. J Exp Med. 2022. PMID: 36048016 Free PMC article.
Prospective validation of the PML risk biomarker l-selectin and influence of natalizumab extended intervals.
Schwab N, Schneider-Hohendorf T, Pignolet B, Bucciarelli F, Scandella L, Ciron J, Biotti D, Lebrun-Frenay C, Mathey G, Clavelou P, Pelletier J, Ostkamp P, Meinl I, Windhagen S, Klotz L, Gross CC, Meuth SG, Deisenhammer F, Brassat D, Wiendl H; Best-MS Study Group. Schwab N, et al. Among authors: ostkamp p. Neurology. 2019 Sep 17;93(12):550-554. doi: 10.1212/WNL.0000000000008135. Epub 2019 Aug 22. Neurology. 2019. PMID: 31439633 No abstract available.
Human CCR5high effector memory cells perform CNS parenchymal immune surveillance via GZMK-mediated transendothelial diapedesis.
Herich S, Schneider-Hohendorf T, Rohlmann A, Khaleghi Ghadiri M, Schulte-Mecklenbeck A, Zondler L, Janoschka C, Ostkamp P, Richter J, Breuer J, Dimitrov S, Rammensee HG, Grauer OM, Klotz L, Gross CC, Stummer W, Missler M, Zarbock A, Vestweber D, Wiendl H, Schwab N. Herich S, et al. Among authors: ostkamp p. Brain. 2019 Nov 1;142(11):3411-3427. doi: 10.1093/brain/awz301. Brain. 2019. PMID: 31563951
A single-cell analysis framework allows for characterization of CSF leukocytes and their tissue of origin in multiple sclerosis.
Ostkamp P, Deffner M, Schulte-Mecklenbeck A, Wünsch C, Lu IN, Wu GF, Goelz S, De Jager PL, Kuhlmann T, Gross CC, Klotz L, Meyer Zu Hörste G, Wiendl H, Schneider-Hohendorf T, Schwab N. Ostkamp P, et al. Sci Transl Med. 2022 Nov 30;14(673):eadc9778. doi: 10.1126/scitranslmed.adc9778. Epub 2022 Nov 30. Sci Transl Med. 2022. PMID: 36449599
Correction: Broader Epstein-Barr virus-specific T cell receptor repertoire in patients with multiple sclerosis.
Schneider-Hohendorf T, Gerdes LA, Pignolet B, Gittelman R, Ostkamp P, Rubelt F, Raposo C, Tackenberg B, Riepenhausen M, Janoschka C, Wünsch C, Bucciarelli F, Flierl-Hecht A, Beltrán E, Kümpfel T, Anslinger K, Gross CC, Chapman H, Kaplan I, Brassat D, Wekerle H, Kerschensteiner M, Klotz L, Lünemann JD, Hohlfeld R, Liblau R, Wiendl H, Schwab N. Schneider-Hohendorf T, et al. Among authors: ostkamp p. J Exp Med. 2022 Nov 7;219(11):e2022065010252022c. doi: 10.1084/jem.2022065010252022c. Epub 2022 Oct 28. J Exp Med. 2022. PMID: 36305889 Free PMC article. No abstract available.