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Concise syntheses and HCV NS5B polymerase inhibition of (2'R)-3 and (2'S)-2'-ethynyluridine-10 and related nucleosides.
Bennett F, Buevich AV, Huang HC, Girijavallabhan V, Kerekes AD, Huang Y, Malikzay A, Smith E, Ferrari E, Senior M, Osterman R, Wang L, Wang J, Pu H, Truong QT, Tawa P, Bogen SL, Davies IW, Weber AE. Bennett F, et al. Among authors: osterman r. Bioorg Med Chem Lett. 2017 Dec 1;27(23):5349-5352. doi: 10.1016/j.bmcl.2017.06.064. Epub 2017 Jun 24. Bioorg Med Chem Lett. 2017. PMID: 29056248
Substituted 4-morpholine N-arylsulfonamides as γ-secretase inhibitors.
Zhao Z, Pissarnitski DA, Josien HB, Bara TA, Clader JW, Li H, McBriar MD, Rajagopalan M, Xu R, Terracina G, Hyde L, Song L, Zhang L, Parker EM, Osterman R, Buevich AV. Zhao Z, et al. Among authors: osterman r. Eur J Med Chem. 2016 Nov 29;124:36-48. doi: 10.1016/j.ejmech.2016.08.024. Epub 2016 Aug 13. Eur J Med Chem. 2016. PMID: 27560281
Adapting services to engage young adults in ICCD clubhouses.
McKay CE, Osterman R, Shaffer J, Sawyer E, Gerrard E, Olivera N. McKay CE, et al. Among authors: osterman r. Psychiatr Rehabil J. 2012 Winter;35(3):181-8. doi: 10.2975/35.3.2012.181.188. Psychiatr Rehabil J. 2012. PMID: 22246116
The application of (Z)-3-aryl-3-haloenoic acids to the synthesis of (Z)-5-benzylidene-4-arylpyrrol-2(5H)-ones.
Gupton JT, Telang N, Banner EJ, Kluball EJ, Hall KE, Finzel KL, Jia X, Bates SR, Welden RS, Giglio BC, Eaton JE, Barelli PJ, Firich LT, Stafford JA, Coppock MB, Worrall EF, Kanters RP, Keertikar K, Osterman R. Gupton JT, et al. Among authors: osterman r. Tetrahedron. 2010 Nov 20;66(47):9113-9122. doi: 10.1016/j.tet.2010.09.080. Tetrahedron. 2010. PMID: 21135918 Free PMC article.
Highly Regioselective Nitration Reactions Provide a Versatile Method of Functionalizing Benzocycloheptapyridine Tricyclic Ring Systems: Application toward Preparation of Nanomolar Inhibitors of Farnesyl Protein Transferase.
Njoroge FG, Vibulbhan B, Pinto P, Chan TM, Osterman R, Remiszewski S, Del Rosario J, Doll R, Girijavallabhan V, Ganguly AK. Njoroge FG, et al. Among authors: osterman r. J Org Chem. 1998 Feb 6;63(3):445-451. doi: 10.1021/jo971100z. J Org Chem. 1998. PMID: 11672031