Oster LM - Search Results

1

Insights into cephamycin biosynthesis: the crystal structure of CmcI from Streptomyces clavuligerus.

Oster LM, Lester DR, Terwisscha van Scheltinga A, Svenda M, van Lun M, Généreux C, Andersson I. Oster LM, et al. J Mol Biol. 2006 Apr 28;358(2):546-58. doi: 10.1016/j.jmb.2006.02.004. Epub 2006 Feb 21. J Mol Biol. 2006. PMID: 16527306

2

The structural basis of cephalosporin formation in a mononuclear ferrous enzyme.

Valegård K, Terwisscha van Scheltinga AC, Dubus A, Ranghino G, Oster LM, Hajdu J, Andersson I. Valegård K, et al. Among authors: oster lm. Nat Struct Mol Biol. 2004 Jan;11(1):95-101. doi: 10.1038/nsmb712. Epub 2003 Dec 29. Nat Struct Mol Biol. 2004. PMID: 14718929

3

Expression, purification, crystallization and preliminary X-ray diffraction studies of the cmcI component of Streptomyces clavuligerus 7alpha-cephem-methoxylase.

Lester DR, Oster LM, Svenda M, Andersson I. Lester DR, et al. Among authors: oster lm. Acta Crystallogr D Biol Crystallogr. 2004 Sep;60(Pt 9):1618-21. doi: 10.1107/S090744490401666X. Epub 2004 Aug 26. Acta Crystallogr D Biol Crystallogr. 2004. PMID: 15333935

4

Conformational flexibility of the C terminus with implications for substrate binding and catalysis revealed in a new crystal form of deacetoxycephalosporin C synthase.

Oster LM, van Scheltinga AC, Valegård K, Hose AM, Dubus A, Hajdu J, Andersson I. Oster LM, et al. J Mol Biol. 2004 Oct 8;343(1):157-71. doi: 10.1016/j.jmb.2004.07.049. J Mol Biol. 2004. PMID: 15381427

5

A class of highly selective inhibitors bind to an active state of PI3Kγ.

Gangadhara G, Dahl G, Bohnacker T, Rae R, Gunnarsson J, Blaho S, Öster L, Lindmark H, Karabelas K, Pemberton N, Tyrchan C, Mogemark M, Wymann MP, Williams RL, Perry MWD, Papavoine T, Petersen J. Gangadhara G, et al. Nat Chem Biol. 2019 Apr;15(4):348-357. doi: 10.1038/s41589-018-0215-0. Epub 2019 Feb 4. Nat Chem Biol. 2019. PMID: 30718815

6

FAM3B PANDER and FAM3C ILEI represent a distinct class of signaling molecules with a non-cytokine-like fold.

Johansson P, Bernström J, Gorman T, Oster L, Bäckström S, Schweikart F, Xu B, Xue Y, Schiavone LH. Johansson P, et al. Structure. 2013 Feb 5;21(2):306-13. doi: 10.1016/j.str.2012.12.009. Epub 2013 Jan 17. Structure. 2013. PMID: 23333428 Free article.

7

Heme ligation and conformational plasticity in the isolated c domain of cytochrome cd1 nitrite reductase.

Steensma E, Gordon E, Oster LM, Ferguson SJ, Hajdu J. Steensma E, et al. Among authors: oster lm. J Biol Chem. 2001 Feb 23;276(8):5846-55. doi: 10.1074/jbc.M007345200. Epub 2000 Oct 16. J Biol Chem. 2001. PMID: 11035020 Free article.

8

Discovery of triazole aminopyrazines as a highly potent and selective series of PI3Kδ inhibitors.

Terstiege I, Perry M, Petersen J, Tyrchan C, Svensson T, Lindmark H, Öster L. Terstiege I, et al. Bioorg Med Chem Lett. 2017 Feb 1;27(3):679-687. doi: 10.1016/j.bmcl.2016.11.004. Epub 2016 Nov 2. Bioorg Med Chem Lett. 2017. PMID: 28017532

9

Design and Synthesis of Soluble and Cell-Permeable PI3Kδ Inhibitors for Long-Acting Inhaled Administration.

Perry MWD, Björhall K, Bonn B, Carlsson J, Chen Y, Eriksson A, Fredlund L, Hao H, Holden NS, Karabelas K, Lindmark H, Liu F, Pemberton N, Petersen J, Rodrigo Blomqvist S, Smith RW, Svensson T, Terstiege I, Tyrchan C, Yang W, Zhao S, Öster L. Perry MWD, et al. J Med Chem. 2017 Jun 22;60(12):5057-5071. doi: 10.1021/acs.jmedchem.7b00401. Epub 2017 Jun 7. J Med Chem. 2017. PMID: 28520415 Free article.

10

Discovery of Highly Isoform Selective Orally Bioavailable Phosphoinositide 3-Kinase (PI3K)-γ Inhibitors.

Pemberton N, Mogemark M, Arlbrandt S, Bold P, Cox RJ, Gardelli C, Holden NS, Karabelas K, Karlsson J, Lever S, Li X, Lindmark H, Norberg M, Perry MWD, Petersen J, Rodrigo Blomqvist S, Thomas M, Tyrchan C, Westin Eriksson A, Zlatoidsky P, Öster L. Pemberton N, et al. J Med Chem. 2018 Jun 28;61(12):5435-5441. doi: 10.1021/acs.jmedchem.8b00447. Epub 2018 Jun 18. J Med Chem. 2018. PMID: 29852070

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