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Host monitoring of quorum sensing during Pseudomonas aeruginosa infection.
Moura-Alves P, Puyskens A, Stinn A, Klemm M, Guhlich-Bornhof U, Dorhoi A, Furkert J, Kreuchwig A, Protze J, Lozza L, Pei G, Saikali P, Perdomo C, Mollenkopf HJ, Hurwitz R, Kirschhoefer F, Brenner-Weiss G, Weiner J 3rd, Oschkinat H, Kolbe M, Krause G, Kaufmann SHE. Moura-Alves P, et al. Among authors: oschkinat h. Science. 2019 Dec 20;366(6472):eaaw1629. doi: 10.1126/science.aaw1629. Science. 2019. PMID: 31857448
Discovery of low-molecular-weight ligands for the AF6 PDZ domain.
Joshi M, Vargas C, Boisguerin P, Diehl A, Krause G, Schmieder P, Moelling K, Hagen V, Schade M, Oschkinat H. Joshi M, et al. Among authors: oschkinat h. Angew Chem Int Ed Engl. 2006 Jun 2;45(23):3790-5. doi: 10.1002/anie.200503965. Angew Chem Int Ed Engl. 2006. PMID: 16671149 No abstract available.
Antigen 85C inhibition restricts Mycobacterium tuberculosis growth through disruption of cord factor biosynthesis.
Warrier T, Tropis M, Werngren J, Diehl A, Gengenbacher M, Schlegel B, Schade M, Oschkinat H, Daffe M, Hoffner S, Eddine AN, Kaufmann SH. Warrier T, et al. Among authors: oschkinat h. Antimicrob Agents Chemother. 2012 Apr;56(4):1735-43. doi: 10.1128/AAC.05742-11. Epub 2012 Jan 30. Antimicrob Agents Chemother. 2012. PMID: 22290959 Free PMC article.
Small-molecule inhibitors of AF6 PDZ-mediated protein-protein interactions.
Vargas C, Radziwill G, Krause G, Diehl A, Keller S, Kamdem N, Czekelius C, Kreuchwig A, Schmieder P, Doyle D, Moelling K, Hagen V, Schade M, Oschkinat H. Vargas C, et al. Among authors: oschkinat h. ChemMedChem. 2014 Jul;9(7):1458-62. doi: 10.1002/cmdc.201300553. Epub 2014 Mar 25. ChemMedChem. 2014. PMID: 24668962
AhR sensing of bacterial pigments regulates antibacterial defence.
Moura-Alves P, Faé K, Houthuys E, Dorhoi A, Kreuchwig A, Furkert J, Barison N, Diehl A, Munder A, Constant P, Skrahina T, Guhlich-Bornhof U, Klemm M, Koehler AB, Bandermann S, Goosmann C, Mollenkopf HJ, Hurwitz R, Brinkmann V, Fillatreau S, Daffe M, Tümmler B, Kolbe M, Oschkinat H, Krause G, Kaufmann SH. Moura-Alves P, et al. Among authors: oschkinat h. Nature. 2014 Aug 28;512(7515):387-92. doi: 10.1038/nature13684. Epub 2014 Aug 13. Nature. 2014. PMID: 25119038
Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin.
Belyy A, Lindemann F, Roderer D, Funk J, Bardiaux B, Protze J, Bieling P, Oschkinat H, Raunser S. Belyy A, et al. Among authors: oschkinat h. Nat Commun. 2022 Jul 20;13(1):4202. doi: 10.1038/s41467-022-31836-w. Nat Commun. 2022. PMID: 35858890 Free PMC article.
Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling.
Kamdem N, Roske Y, Kovalskyy D, Platonov MO, Balinskyi O, Kreuchwig A, Saupe J, Fang L, Diehl A, Schmieder P, Krause G, Rademann J, Heinemann U, Birchmeier W, Oschkinat H. Kamdem N, et al. Among authors: oschkinat h. Magn Reson (Gott). 2021 Jun 2;2(1):355-374. doi: 10.5194/mr-2-355-2021. eCollection 2021. Magn Reson (Gott). 2021. PMID: 37904770 Free PMC article.
224 results