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Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis.
Guo M, Chan THM, Zhou Q, An O, Li Y, Song Y, Tan ZH, Ng VHE, Peramangalam PS, Tan ZQ, Cao X, Iwanaga E, Matsuoka M, Ooi MGM, Jen WY, Koh LP, Chan E, Tan LK, Goh Y, Wang W, Koh BTH, Chun CM, Fullwood MJ, Chng WJ, Osato M, Pulikkan JA, Yang H, Chen L, Tenen DG. Guo M, et al. Among authors: osato m. Blood. 2023 Jun 22;141(25):3078-3090. doi: 10.1182/blood.2022015830. Blood. 2023. PMID: 36796022
Heterozygous PU.1 mutations are associated with acute myeloid leukemia.
Mueller BU, Pabst T, Osato M, Asou N, Johansen LM, Minden MD, Behre G, Hiddemann W, Ito Y, Tenen DG. Mueller BU, et al. Among authors: osato m. Blood. 2002 Aug 1;100(3):998-1007. doi: 10.1182/blood.v100.3.998. Blood. 2002. PMID: 12130514 Free article.
Heterozygous PU.1 mutations are associated with acute myeloid leukemia.
Mueller BU, Pabst T, Osato M, Asou N, Johansen LM, Minden MD, Behre G, Hiddemann W, Ito Y, Tenen DG. Mueller BU, et al. Among authors: osato m. Blood. 2003 Mar 1;101(5):2074. doi: 10.1182/blood-2002-12-3903. Blood. 2003. PMID: 12584148 Free article. No abstract available.
The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations.
Huang G, Zhao X, Wang L, Elf S, Xu H, Zhao X, Sashida G, Zhang Y, Liu Y, Lee J, Menendez S, Yang Y, Yan X, Zhang P, Tenen DG, Osato M, Hsieh JJ, Nimer SD. Huang G, et al. Among authors: osato m. Blood. 2011 Dec 15;118(25):6544-52. doi: 10.1182/blood-2010-11-317909. Epub 2011 Oct 19. Blood. 2011. PMID: 22012064 Free PMC article.
An unsung runt 6e isoform for HSC expansion.
Osato M. Osato M. Blood. 2014 Jun 12;123(24):3684-6. doi: 10.1182/blood-2014-05-572891. Blood. 2014. PMID: 24926066 Free article. No abstract available.
Lysine acetyltransferase Tip60 is required for hematopoietic stem cell maintenance.
Numata A, Kwok HS, Zhou QL, Li J, Tirado-Magallanes R, Angarica VE, Hannah R, Park J, Wang CQ, Krishnan V, Rajagopalan D, Zhang Y, Zhou S, Welner RS, Osato M, Jha S, Bohlander SK, Göttgens B, Yang H, Benoukraf T, Lough JW, Bararia D, Tenen DG. Numata A, et al. Among authors: osato m. Blood. 2020 Oct 8;136(15):1735-1747. doi: 10.1182/blood.2019001279. Blood. 2020. PMID: 32542325 Free PMC article.
247 results