Ortuno JC - Search Results

1

Synthesis of Bleomycin-Inspired RNA Ligands Targeting the Biogenesis of Oncogenic miRNAs.

Maucort C, Bonnet M, Ortuno JC, Tucker G, Quissac E, Verreault M, Azoulay S, Di Giorgio C, Di Giorgio A, Duca M. Maucort C, et al. Among authors: ortuno jc. J Med Chem. 2023 Aug 10;66(15):10639-10657. doi: 10.1021/acs.jmedchem.3c00797. Epub 2023 Jul 14. J Med Chem. 2023. PMID: 37449818

2

Parallel liquid synthesis of N,N'-Disubstituted 3-amino azepin-2-ones as potent and specific farnesyl transferase inhibitors.

Le Diguarher T, Ortuno JC, Dorey G, Shanks D, Guilbaud N, Pierré A, Fauchère JL, Hickman JA, Tucker GC, Casara PJ. Le Diguarher T, et al. Among authors: ortuno jc. Bioorg Med Chem. 2003 Jul 17;11(14):3193-204. doi: 10.1016/s0968-0896(03)00218-9. Bioorg Med Chem. 2003. PMID: 12818682

3

Synthesis of N,N'-disubstituted 3-aminobenzo[c] and [d]azepin-2-ones as potent and specific farnesyl transferase inhibitors.

Le Diguarher T, Ortuno JC, Shanks D, Guilbaud N, Pierré A, Raimbaud E, Fauchère JL, Hickman JA, Tucker GC, Casara PJ. Le Diguarher T, et al. Among authors: ortuno jc. Bioorg Med Chem Lett. 2004 Feb 9;14(3):767-71. doi: 10.1016/j.bmcl.2003.11.013. Bioorg Med Chem Lett. 2004. PMID: 14741286

4

Design and synthesis of novel N-sulfonyl-2-indoles that behave as 5-HT₆ receptor ligands with significant selectivity for D₃ over D₂ receptors.

Saavedra OM, Karila D, Brossard D, Rojas A, Dupuis D, Gohier A, Mannoury la Cour C, Millan MJ, Ortuno JC, Hanessian S. Saavedra OM, et al. Among authors: ortuno jc. Bioorg Med Chem. 2017 Jan 1;25(1):38-52. doi: 10.1016/j.bmc.2016.10.010. Epub 2016 Oct 12. Bioorg Med Chem. 2017. PMID: 28029458

5

Synthesis of Functionalized 1H-Isochromene Derivatives via a Au-Catalyzed Domino Cycloisomerization/Reduction Approach.

Tomás-Mendivil E, Starck J, Ortuno JC, Michelet V. Tomás-Mendivil E, et al. Among authors: ortuno jc. Org Lett. 2015 Dec 18;17(24):6126-9. doi: 10.1021/acs.orglett.5b03146. Epub 2015 Nov 25. Org Lett. 2015. PMID: 26602612

6

Approach to the specificity and selectivity between D2 and D3 receptors by mutagenesis and binding experiments part I: Expression and characterization of D2 and D3 receptor mutants.

Legros C, Rojas A, Dupré C, Brasseur C, Riest-Fery I, Muller O, Ortuno JC, Nosjean O, Guenin SP, Ferry G, Boutin JA. Legros C, et al. Among authors: ortuno jc. Protein Sci. 2022 Dec;31(12):e4459. doi: 10.1002/pro.4459. Protein Sci. 2022. PMID: 36177735 Free PMC article.

7

S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab.

Burbridge MF, Bossard CJ, Saunier C, Fejes I, Bruno A, Léonce S, Ferry G, Da Violante G, Bouzom F, Cattan V, Jacquet-Bescond A, Comoglio PM, Lockhart BP, Boutin JA, Cordi A, Ortuno JC, Pierré A, Hickman JA, Cruzalegui FH, Depil S. Burbridge MF, et al. Among authors: ortuno jc. Mol Cancer Ther. 2013 Sep;12(9):1749-62. doi: 10.1158/1535-7163.MCT-13-0075. Epub 2013 Jun 26. Mol Cancer Ther. 2013. PMID: 23804704

8

Dual-acting agents for improving cognition and real-world function in Alzheimer's disease: Focus on 5-HT6 and D3 receptors as hubs.

Millan MJ, Dekeyne A, Gobert A, Brocco M, Mannoury la Cour C, Ortuno JC, Watson D, Fone KCF. Millan MJ, et al. Among authors: ortuno jc. Neuropharmacology. 2020 Oct 15;177:108099. doi: 10.1016/j.neuropharm.2020.108099. Epub 2020 Jun 7. Neuropharmacology. 2020. PMID: 32525060 Review.

9

The melanin-concentrating hormone1 receptor antagonists, SNAP-7941 and GW3430, enhance social recognition and dialysate levels of acetylcholine in the frontal cortex of rats.

Millan MJ, Gobert A, Panayi F, Rivet JM, Dekeyne A, Brocco M, Ortuno JC, Di Cara B. Millan MJ, et al. Among authors: ortuno jc. Int J Neuropsychopharmacol. 2008 Dec;11(8):1105-22. doi: 10.1017/S1461145708008894. Epub 2008 May 9. Int J Neuropsychopharmacol. 2008. PMID: 18466669 Free article.

10

Safety and efficacy of a feed additive consisting of a zinc(II)-betaine complex for all animal species (Biochem Zusatzstoffe Handels- und Produktionsges. mbH).

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP); Bampidis V, Azimonti G, Bastos ML, Christensen H, Dusemund B, Durjava M, Kouba M, López-Alonso M, Puente SL, Marcon F, Mayo B, Pechová A, Petkova M, Ramos F, Sanz Y, Villa RE, Woutersen R, Finizio A, Poiger T, Teodorovic I, Anguita M, Galobart J, Holczknecht O, Innocenti ML, Ortuno JC, Manini P, Pizzo F, Radovnikovic A, Vettori MV, Amaduzzi A. EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), et al. Among authors: ortuno jc. EFSA J. 2023 Feb 21;21(2):e07819. doi: 10.2903/j.efsa.2023.7819. eCollection 2023 Feb. EFSA J. 2023. PMID: 36824682 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

12 results

Search Page