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The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes.
Lu TT, Heyne S, Dror E, Casas E, Leonhardt L, Boenke T, Yang CH, Sagar, Arrigoni L, Dalgaard K, Teperino R, Enders L, Selvaraj M, Ruf M, Raja SJ, Xie H, Boenisch U, Orkin SH, Lynn FC, Hoffman BG, Grün D, Vavouri T, Lempradl AM, Pospisilik JA. Lu TT, et al. Among authors: orkin sh. Cell Metab. 2018 Jun 5;27(6):1294-1308.e7. doi: 10.1016/j.cmet.2018.04.013. Epub 2018 May 10. Cell Metab. 2018. PMID: 29754954 Free PMC article.
Immunology: changed destiny.
Xie H, Orkin SH. Xie H, et al. Among authors: orkin sh. Nature. 2007 Sep 27;449(7161):410-1. doi: 10.1038/449410a. Nature. 2007. PMID: 17898754 No abstract available.
Polycomb repressive complex 2 regulates normal development of the mouse heart.
He A, Ma Q, Cao J, von Gise A, Zhou P, Xie H, Zhang B, Hsing M, Christodoulou DC, Cahan P, Daley GQ, Kong SW, Orkin SH, Seidman CE, Seidman JG, Pu WT. He A, et al. Among authors: orkin sh. Circ Res. 2012 Feb 3;110(3):406-15. doi: 10.1161/CIRCRESAHA.111.252205. Epub 2011 Dec 8. Circ Res. 2012. PMID: 22158708 Free PMC article.
Polycomb repressive complex 2 is required for MLL-AF9 leukemia.
Neff T, Sinha AU, Kluk MJ, Zhu N, Khattab MH, Stein L, Xie H, Orkin SH, Armstrong SA. Neff T, et al. Among authors: orkin sh. Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):5028-33. doi: 10.1073/pnas.1202258109. Epub 2012 Mar 6. Proc Natl Acad Sci U S A. 2012. PMID: 22396593 Free PMC article.
652 results