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Page 1
Benzimidazole Derivatives as New and Selective Inhibitors of Arginase from Leishmania mexicana with Biological Activity against Promastigotes and Amastigotes.
Betancourt-Conde I, Avitia-Domínguez C, Hernández-Campos A, Castillo R, Yépez-Mulia L, Oria-Hernández J, Méndez ST, Sierra-Campos E, Valdez-Solana M, Martínez-Caballero S, Hermoso JA, Romo-Mancillas A, Téllez-Valencia A. Betancourt-Conde I, et al. Among authors: oria hernandez j. Int J Mol Sci. 2021 Dec 19;22(24):13613. doi: 10.3390/ijms222413613. Int J Mol Sci. 2021. PMID: 34948408 Free PMC article.
Determining the molecular mechanism of inactivation by chemical modification of triosephosphate isomerase from the human parasite Giardia lamblia: a study for antiparasitic drug design.
Enríquez-Flores S, Rodríguez-Romero A, Hernández-Alcántara G, Oria-Hernández J, Gutiérrez-Castrellón P, Pérez-Hernández G, de la Mora-de la Mora I, Castillo-Villanueva A, García-Torres I, Méndez ST, Gómez-Manzo S, Torres-Arroyo A, López-Velázquez G, Reyes-Vivas H. Enríquez-Flores S, et al. Proteins. 2011 Sep;79(9):2711-24. doi: 10.1002/prot.23100. Epub 2011 Jul 22. Proteins. 2011. PMID: 21786322
Structural and functional perturbation of Giardia lamblia triosephosphate isomerase by modification of a non-catalytic, non-conserved region.
Hernández-Alcántara G, Torres-Larios A, Enríquez-Flores S, García-Torres I, Castillo-Villanueva A, Méndez ST, de la Mora-de la Mora I, Gómez-Manzo S, Torres-Arroyo A, López-Velázquez G, Reyes-Vivas H, Oria-Hernández J. Hernández-Alcántara G, et al. PLoS One. 2013 Jul 22;8(7):e69031. doi: 10.1371/journal.pone.0069031. Print 2013. PLoS One. 2013. PMID: 23894402 Free PMC article.
The E104D mutation increases the susceptibility of human triosephosphate isomerase to proteolysis. Asymmetric cleavage of the two monomers of the homodimeric enzyme.
De La Mora-De La Mora I, Torres-Larios A, Mendoza-Hernández G, Enriquez-Flores S, Castillo-Villanueva A, Mendez ST, Garcia-Torres I, Torres-Arroyo A, Gómez-Manzo S, Marcial-Quino J, Oria-Hernández J, López-Velázquez G, Reyes-Vivas H. De La Mora-De La Mora I, et al. Biochim Biophys Acta. 2013 Dec;1834(12):2702-11. doi: 10.1016/j.bbapap.2013.08.012. Epub 2013 Sep 20. Biochim Biophys Acta. 2013. PMID: 24056040
Giardial triosephosphate isomerase as possible target of the cytotoxic effect of omeprazole in Giardia lamblia.
Reyes-Vivas H, de la Mora-de la Mora I, Castillo-Villanueva A, Yépez-Mulia L, Hernández-Alcántara G, Figueroa-Salazar R, García-Torres I, Gómez-Manzo S, Méndez ST, Vanoye-Carlo A, Marcial-Quino J, Torres-Arroyo A, Oria-Hernández J, Gutiérrez-Castrellón P, Enríquez-Flores S, López-Velázquez G. Reyes-Vivas H, et al. Antimicrob Agents Chemother. 2014 Dec;58(12):7072-82. doi: 10.1128/AAC.02900-14. Epub 2014 Sep 15. Antimicrob Agents Chemother. 2014. PMID: 25223993 Free PMC article.
Synthesis of nitro(benzo)thiazole acetamides and in vitro antiprotozoal effect against amitochondriate parasites Giardia intestinalis and Trichomonas vaginalis.
Navarrete-Vázquez G, Chávez-Silva F, Colín-Lozano B, Estrada-Soto S, Hidalgo-Figueroa S, Guerrero-Álvarez J, Méndez ST, Reyes-Vivas H, Oria-Hernández J, Canul-Canché J, Ortiz-Andrade R, Moo-Puc R. Navarrete-Vázquez G, et al. Bioorg Med Chem. 2015 May 1;23(9):2204-10. doi: 10.1016/j.bmc.2015.02.059. Epub 2015 Mar 10. Bioorg Med Chem. 2015. PMID: 25801157
Novel giardicidal compounds bearing proton pump inhibitor scaffold proceeding through triosephosphate isomerase inactivation.
Hernández-Ochoa B, Navarrete-Vázquez G, Nava-Zuazo C, Castillo-Villanueva A, Méndez ST, Torres-Arroyo A, Gómez-Manzo S, Marcial-Quino J, Ponce-Macotela M, Rufino-González Y, Martínez-Gordillo M, Palencia-Hernández G, Esturau-Escofet N, Calderon-Jaimes E, Oria-Hernández J, Reyes-Vivas H. Hernández-Ochoa B, et al. Sci Rep. 2017 Aug 10;7(1):7810. doi: 10.1038/s41598-017-07612-y. Sci Rep. 2017. PMID: 28798383 Free PMC article.
Species-Specific Inactivation of Triosephosphate Isomerase from Trypanosoma brucei: Kinetic and Molecular Dynamics Studies.
Vázquez-Raygoza A, Cano-González L, Velázquez-Martínez I, Trejo-Soto PJ, Castillo R, Hernández-Campos A, Hernández-Luis F, Oria-Hernández J, Castillo-Villanueva A, Avitia-Domínguez C, Sierra-Campos E, Valdez-Solana M, Téllez-Valencia A. Vázquez-Raygoza A, et al. Molecules. 2017 Nov 24;22(12):2055. doi: 10.3390/molecules22122055. Molecules. 2017. PMID: 29186784 Free PMC article.
Biochemical, Kinetic, and Computational Structural Characterization of Shikimate Kinase from Methicillin-Resistant Staphylococcus aureus.
Favela-Candia A, Téllez-Valencia A, Campos-Almazán M, Sierra-Campos E, Valdez-Solana M, Oria-Hernández J, Castillo-Villanueva A, Nájera H, Avitia-Domínguez C. Favela-Candia A, et al. Among authors: oria hernandez j. Mol Biotechnol. 2019 Apr;61(4):274-285. doi: 10.1007/s12033-019-00159-5. Mol Biotechnol. 2019. PMID: 30747382
33 results