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Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression.
Agudelo LZ, Femenía T, Orhan F, Porsmyr-Palmertz M, Goiny M, Martinez-Redondo V, Correia JC, Izadi M, Bhat M, Schuppe-Koistinen I, Pettersson AT, Ferreira DMS, Krook A, Barres R, Zierath JR, Erhardt S, Lindskog M, Ruas JL. Agudelo LZ, et al. Among authors: orhan f. Cell. 2014 Sep 25;159(1):33-45. doi: 10.1016/j.cell.2014.07.051. Cell. 2014. PMID: 25259918 Free article.
Behavioral disturbances in adult mice following neonatal virus infection or kynurenine treatment--role of brain kynurenic acid.
Liu XC, Holtze M, Powell SB, Terrando N, Larsson MK, Persson A, Olsson SK, Orhan F, Kegel M, Asp L, Goiny M, Schwieler L, Engberg G, Karlsson H, Erhardt S. Liu XC, et al. Among authors: orhan f. Brain Behav Immun. 2014 Feb;36:80-9. doi: 10.1016/j.bbi.2013.10.010. Epub 2013 Oct 17. Brain Behav Immun. 2014. PMID: 24140727 Free PMC article.
Increased levels of IL-6 in the cerebrospinal fluid of patients with chronic schizophrenia--significance for activation of the kynurenine pathway.
Schwieler L, Larsson MK, Skogh E, Kegel ME, Orhan F, Abdelmoaty S, Finn A, Bhat M, Samuelsson M, Lundberg K, Dahl ML, Sellgren C, Schuppe-Koistinen I, Svensson C, Erhardt S, Engberg G. Schwieler L, et al. Among authors: orhan f. J Psychiatry Neurosci. 2015 Mar;40(2):126-33. doi: 10.1503/jpn.140126. J Psychiatry Neurosci. 2015. PMID: 25455350 Free PMC article.
Repeated LPS Injection Induces Distinct Changes in the Kynurenine Pathway in Mice.
Larsson MK, Faka A, Bhat M, Imbeault S, Goiny M, Orhan F, Oliveros A, Ståhl S, Liu XC, Choi DS, Sandberg K, Engberg G, Schwieler L, Erhardt S. Larsson MK, et al. Among authors: orhan f. Neurochem Res. 2016 Sep;41(9):2243-55. doi: 10.1007/s11064-016-1939-4. Epub 2016 May 10. Neurochem Res. 2016. PMID: 27165635
CSF GABA is reduced in first-episode psychosis and associates to symptom severity.
Orhan F, Fatouros-Bergman H, Goiny M, Malmqvist A, Piehl F; Karolinska Schizophrenia Project (KaSP) Consortium; Cervenka S, Collste K, Victorsson P, Sellgren CM, Flyckt L, Erhardt S, Engberg G. Orhan F, et al. Mol Psychiatry. 2018 May;23(5):1244-1250. doi: 10.1038/mp.2017.25. Epub 2017 Mar 14. Mol Psychiatry. 2018. PMID: 28289277 Free PMC article.
Increased peripheral levels of TARC/CCL17 in first episode psychosis patients.
Malmqvist A, Schwieler L, Orhan F, Fatouros-Bergman H, Bauer M, Flyckt L, Cervenka S, Engberg G, Piehl F; Karolinska Schizophrenia Project (KaSP) consortium; Erhardt S. Malmqvist A, et al. Among authors: orhan f. Schizophr Res. 2019 Aug;210:221-227. doi: 10.1016/j.schres.2018.12.033. Epub 2019 Jan 3. Schizophr Res. 2019. PMID: 30612841
152 results