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Early Infiltration of Innate Immune Cells to the Liver Depletes HNF4α and Promotes Extrahepatic Carcinogenesis.
Goldman O, Adler LN, Hajaj E, Croese T, Darzi N, Galai S, Tishler H, Ariav Y, Lavie D, Fellus-Alyagor L, Oren R, Kuznetsov Y, David E, Jaschek R, Stossel C, Singer O, Malitsky S, Barak R, Seger R, Erez N, Amit I, Tanay A, Saada A, Golan T, Rubinek T, Sang Lee J, Ben-Shachar S, Wolf I, Erez A. Goldman O, et al. Among authors: oren r. Cancer Discov. 2023 Jul 7;13(7):1616-1635. doi: 10.1158/2159-8290.CD-22-1062. Cancer Discov. 2023. PMID: 36972357 Free PMC article.
Targeting purine synthesis in ASS1-expressing tumors enhances the response to immune checkpoint inhibitors.
Keshet R, Lee JS, Adler L, Iraqi M, Ariav Y, Lim LQJ, Lerner S, Rabinovich S, Oren R, Katzir R, Weiss Tishler H, Stettner N, Goldman O, Landesman H, Galai S, Kuperman Y, Kuznetsov Y, Brandis A, Mehlman T, Malitsky S, Itkin M, Koehler SE, Zhao Y, Talsania K, Shen TW, Peled N, Ulitsky I, Porgador A, Ruppin E, Erez A. Keshet R, et al. Among authors: oren r. Nat Cancer. 2020 Sep;1(9):894-908. doi: 10.1038/s43018-020-0106-7. Epub 2020 Aug 31. Nat Cancer. 2020. PMID: 35121952
Whole Organ Blood and Lymphatic Vessels Imaging (WOBLI).
Oren R, Fellus-Alyagor L, Addadi Y, Bochner F, Gutman H, Blumenreich S, Dafni H, Dekel N, Neeman M, Lazar S. Oren R, et al. Sci Rep. 2018 Jan 23;8(1):1412. doi: 10.1038/s41598-018-19663-w. Sci Rep. 2018. PMID: 29362484 Free PMC article.
Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas.
Harpaz N, Mittelman T, Beresh O, Griess O, Furth N, Salame TM, Oren R, Fellus-Alyagor L, Harmelin A, Alexandrescu S, Marques JG, Filbin MG, Ron G, Shema E. Harpaz N, et al. Among authors: oren r. Mol Cell. 2022 Jul 21;82(14):2696-2713.e9. doi: 10.1016/j.molcel.2022.05.023. Epub 2022 Jun 17. Mol Cell. 2022. PMID: 35716669 Free article.
Sulfamate Acetamides as Self-Immolative Electrophiles for Covalent Ligand-Directed Release Chemistry.
Reddi RN, Rogel A, Gabizon R, Rawale DG, Harish B, Marom S, Tivon B, Arbel YS, Gurwicz N, Oren R, David K, Liu J, Duberstein S, Itkin M, Malitsky S, Barr H, Katz BZ, Herishanu Y, Shachar I, Shulman Z, London N. Reddi RN, et al. Among authors: oren r. J Am Chem Soc. 2023 Feb 15;145(6):3346-3360. doi: 10.1021/jacs.2c08853. Epub 2023 Feb 4. J Am Chem Soc. 2023. PMID: 36738297 Free PMC article.
382 results