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Palmitoylation of huntingtin by HIP14 is essential for its trafficking and function.
Yanai A, Huang K, Kang R, Singaraja RR, Arstikaitis P, Gan L, Orban PC, Mullard A, Cowan CM, Raymond LA, Drisdel RC, Green WN, Ravikumar B, Rubinsztein DC, El-Husseini A, Hayden MR. Yanai A, et al. Among authors: orban pc. Nat Neurosci. 2006 Jun;9(6):824-31. doi: 10.1038/nn1702. Epub 2006 May 14. Nat Neurosci. 2006. PMID: 16699508 Free PMC article.
Als2-deficient mice exhibit disturbances in endosome trafficking associated with motor behavioral abnormalities.
Devon RS, Orban PC, Gerrow K, Barbieri MA, Schwab C, Cao LP, Helm JR, Bissada N, Cruz-Aguado R, Davidson TL, Witmer J, Metzler M, Lam CK, Tetzlaff W, Simpson EM, McCaffery JM, El-Husseini AE, Leavitt BR, Hayden MR. Devon RS, et al. Among authors: orban pc. Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9595-600. doi: 10.1073/pnas.0510197103. Epub 2006 Jun 12. Proc Natl Acad Sci U S A. 2006. PMID: 16769894 Free PMC article.
Chapter 15 Juvenile amyotrophic lateral sclerosis.
Orban P, Devon RS, Hayden MR, Leavitt BR. Orban P, et al. Handb Clin Neurol. 2007;82:301-12. doi: 10.1016/S0072-9752(07)80018-2. Handb Clin Neurol. 2007. PMID: 18808900
Synaptic dysfunction in progranulin-deficient mice.
Petkau TL, Neal SJ, Milnerwood A, Mew A, Hill AM, Orban P, Gregg J, Lu G, Feldman HH, Mackenzie IR, Raymond LA, Leavitt BR. Petkau TL, et al. Neurobiol Dis. 2012 Feb;45(2):711-22. doi: 10.1016/j.nbd.2011.10.016. Epub 2011 Oct 25. Neurobiol Dis. 2012. PMID: 22062772
Progranulin expression in the developing and adult murine brain.
Petkau TL, Neal SJ, Orban PC, MacDonald JL, Hill AM, Lu G, Feldman HH, Mackenzie IR, Leavitt BR. Petkau TL, et al. Among authors: orban pc. J Comp Neurol. 2010 Oct 1;518(19):3931-47. doi: 10.1002/cne.22430. J Comp Neurol. 2010. PMID: 20737593
The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs.
Allan SE, Passerini L, Bacchetta R, Crellin N, Dai M, Orban PC, Ziegler SF, Roncarolo MG, Levings MK. Allan SE, et al. Among authors: orban pc. J Clin Invest. 2005 Nov;115(11):3276-84. doi: 10.1172/JCI24685. Epub 2005 Oct 6. J Clin Invest. 2005. PMID: 16211090 Free PMC article.
42 results