Orange JS - Search Results

1

A novel missense mutation in the nuclear factor-κB essential modulator (NEMO) gene resulting in impaired activation of the NF-κB pathway and a unique clinical phenotype presenting as MRSA subdural empyema.

Devora GA, Sun L, Chen Z, van Oers NS, Hanson EP, Orange JS, de la Morena MT. Devora GA, et al. Among authors: orange js. J Clin Immunol. 2010 Nov;30(6):881-5. doi: 10.1007/s10875-010-9445-y. Epub 2010 Jul 23. J Clin Immunol. 2010. PMID: 20652730 Free PMC article.

2

Deficient natural killer cell cytotoxicity in patients with IKK-gamma/NEMO mutations.

Orange JS, Brodeur SR, Jain A, Bonilla FA, Schneider LC, Kretschmer R, Nurko S, Rasmussen WL, Köhler JR, Gellis SE, Ferguson BM, Strominger JL, Zonana J, Ramesh N, Ballas ZK, Geha RS. Orange JS, et al. J Clin Invest. 2002 Jun;109(11):1501-9. doi: 10.1172/JCI14858. J Clin Invest. 2002. PMID: 12045264 Free PMC article.

3

Finding NEMO: genetic disorders of NF-[kappa]B activation.

Orange JS, Geha RS. Orange JS, et al. J Clin Invest. 2003 Oct;112(7):983-5. doi: 10.1172/JCI19960. J Clin Invest. 2003. PMID: 14523034 Free PMC article.

4

The presentation and natural history of immunodeficiency caused by nuclear factor kappaB essential modulator mutation.

Orange JS, Jain A, Ballas ZK, Schneider LC, Geha RS, Bonilla FA. Orange JS, et al. J Allergy Clin Immunol. 2004 Apr;113(4):725-33. doi: 10.1016/j.jaci.2004.01.762. J Allergy Clin Immunol. 2004. PMID: 15100680

5

Human nuclear factor kappa B essential modulator mutation can result in immunodeficiency without ectodermal dysplasia.

Orange JS, Levy O, Brodeur SR, Krzewski K, Roy RM, Niemela JE, Fleisher TA, Bonilla FA, Geha RS. Orange JS, et al. J Allergy Clin Immunol. 2004 Sep;114(3):650-6. doi: 10.1016/j.jaci.2004.06.052. J Allergy Clin Immunol. 2004. PMID: 15356572

6

Human disease resulting from gene mutations that interfere with appropriate nuclear factor-kappaB activation.

Orange JS, Levy O, Geha RS. Orange JS, et al. Immunol Rev. 2005 Feb;203:21-37. doi: 10.1111/j.0105-2896.2005.00221.x. Immunol Rev. 2005. PMID: 15661019 Review.

7

Development of a clinical assay to evaluate toll-like receptor function.

Deering RP, Orange JS. Deering RP, et al. Among authors: orange js. Clin Vaccine Immunol. 2006 Jan;13(1):68-76. doi: 10.1128/CVI.13.1.68-76.2006. Clin Vaccine Immunol. 2006. PMID: 16426002 Free PMC article.

8

NKp30 ligation induces rapid activation of the canonical NF-kappaB pathway in NK cells.

Pandey R, DeStephan CM, Madge LA, May MJ, Orange JS. Pandey R, et al. Among authors: orange js. J Immunol. 2007 Dec 1;179(11):7385-96. doi: 10.4049/jimmunol.179.11.7385. J Immunol. 2007. PMID: 18025182 Free PMC article.

9

IKBKG (nuclear factor-kappa B essential modulator) mutation can be associated with opportunistic infection without impairing Toll-like receptor function.

Salt BH, Niemela JE, Pandey R, Hanson EP, Deering RP, Quinones R, Jain A, Orange JS, Gelfand EW. Salt BH, et al. Among authors: orange js. J Allergy Clin Immunol. 2008 Apr;121(4):976-82. doi: 10.1016/j.jaci.2007.11.014. Epub 2008 Jan 7. J Allergy Clin Immunol. 2008. PMID: 18179816 Free PMC article.

10

Hypomorphic nuclear factor-kappaB essential modulator mutation database and reconstitution system identifies phenotypic and immunologic diversity.

Hanson EP, Monaco-Shawver L, Solt LA, Madge LA, Banerjee PP, May MJ, Orange JS. Hanson EP, et al. Among authors: orange js. J Allergy Clin Immunol. 2008 Dec;122(6):1169-1177.e16. doi: 10.1016/j.jaci.2008.08.018. Epub 2008 Oct 11. J Allergy Clin Immunol. 2008. PMID: 18851874 Free PMC article.

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