Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

67 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Tryptophan depletion sensitizes the AHR pathway by increasing AHR expression and GCN2/LAT1-mediated kynurenine uptake, and potentiates induction of regulatory T lymphocytes.
Solvay M, Holfelder P, Klaessens S, Pilotte L, Stroobant V, Lamy J, Naulaerts S, Spillier Q, Frédérick R, De Plaen E, Sers C, Opitz CA, Van den Eynde BJ, Zhu J. Solvay M, et al. Among authors: opitz ca. J Immunother Cancer. 2023 Jun;11(6):e006728. doi: 10.1136/jitc-2023-006728. J Immunother Cancer. 2023. PMID: 37344101 Free PMC article.
The PI3K and MAPK/p38 pathways control stress granule assembly in a hierarchical manner.
Heberle AM, Razquin Navas P, Langelaar-Makkinje M, Kasack K, Sadik A, Faessler E, Hahn U, Marx-Stoelting P, Opitz CA, Sers C, Heiland I, Schäuble S, Thedieck K. Heberle AM, et al. Among authors: opitz ca. Life Sci Alliance. 2019 Mar 28;2(2):e201800257. doi: 10.26508/lsa.201800257. Print 2019 Apr. Life Sci Alliance. 2019. PMID: 30923191 Free PMC article.
Targeting the aryl hydrocarbon receptor (AhR) with BAY 2416964: a selective small molecule inhibitor for cancer immunotherapy.
Kober C, Roewe J, Schmees N, Roese L, Roehn U, Bader B, Stoeckigt D, Prinz F, Gorjánácz M, Roider HG, Olesch C, Leder G, Irlbacher H, Lesche R, Lefranc J, Oezcan-Wahlbrink M, Batra AS, Elmadany N, Carretero R, Sahm K, Oezen I, Cichon F, Baumann D, Sadik A, Opitz CA, Weinmann H, Hartung IV, Kreft B, Offringa R, Platten M, Gutcher I. Kober C, et al. Among authors: opitz ca. J Immunother Cancer. 2023 Nov;11(11):e007495. doi: 10.1136/jitc-2023-007495. J Immunother Cancer. 2023. PMID: 37963637 Free PMC article.
Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR.
Litzenburger UM, Opitz CA, Sahm F, Rauschenbach KJ, Trump S, Winter M, Ott M, Ochs K, Lutz C, Liu X, Anastasov N, Lehmann I, Höfer T, von Deimling A, Wick W, Platten M. Litzenburger UM, et al. Among authors: opitz ca. Oncotarget. 2014 Feb 28;5(4):1038-51. doi: 10.18632/oncotarget.1637. Oncotarget. 2014. PMID: 24657910 Free PMC article.
The therapeutic potential of targeting tryptophan catabolism in cancer.
Opitz CA, Somarribas Patterson LF, Mohapatra SR, Dewi DL, Sadik A, Platten M, Trump S. Opitz CA, et al. Br J Cancer. 2020 Jan;122(1):30-44. doi: 10.1038/s41416-019-0664-6. Epub 2019 Dec 10. Br J Cancer. 2020. PMID: 31819194 Free PMC article. Review.
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor.
Opitz CA, Litzenburger UM, Sahm F, Ott M, Tritschler I, Trump S, Schumacher T, Jestaedt L, Schrenk D, Weller M, Jugold M, Guillemin GJ, Miller CL, Lutz C, Radlwimmer B, Lehmann I, von Deimling A, Wick W, Platten M. Opitz CA, et al. Nature. 2011 Oct 5;478(7368):197-203. doi: 10.1038/nature10491. Nature. 2011. PMID: 21976023 Free article.
67 results