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Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity.
Fan H, Xia S, Xiang J, Li Y, Ross MO, Lim SA, Yang F, Tu J, Xie L, Dougherty U, Zhang FQ, Zheng Z, Zhang R, Wu R, Dong L, Su R, Chen X, Althaus T, Riedell PA, Jonker PB, Muir A, Lesinski GB, Rafiq S, Dhodapkar MV, Stock W, Odenike O, Patel AA, Opferman J, Tsuji T, Matsuzaki J, Shah H, Faubert B, Elf SE, Layden B, Bissonnette BM, He YY, Kline J, Mao H, Odunsi K, Gao X, Chi H, He C, Chen J. Fan H, et al. Among authors: opferman j. Nature. 2023 Nov;623(7989):1034-1043. doi: 10.1038/s41586-023-06749-3. Epub 2023 Nov 22. Nature. 2023. PMID: 37993715 Free PMC article.
Genetic ablation of Immt induces a lethal disruption of the MICOS complex.
Rockfield SM, Turnis ME, Rodriguez-Enriquez R, Bathina M, Ng SK, Kurtz N, Becerra Mora N, Pelletier S, Robinson CG, Vogel P, Opferman JT. Rockfield SM, et al. Among authors: opferman jt. Life Sci Alliance. 2024 Mar 11;7(6):e202302329. doi: 10.26508/lsa.202302329. Print 2024 Jun. Life Sci Alliance. 2024. PMID: 38467404 Free PMC article.
Correction: Mcl-1 confers protection of Her2-positive breast cancer cells to hypoxia: therapeutic implications.
Bashari MH, Fan F, Vallet S, Sattler M, Arn M, Luckner-Minden C, Schulze-Bergkamen H, Zörnig I, Marme F, Schneeweiss A, Cardone MH, Opferman JT, Jäger D, Podar K. Bashari MH, et al. Among authors: opferman jt. Breast Cancer Res. 2024 Apr 2;26(1):58. doi: 10.1186/s13058-024-01811-y. Breast Cancer Res. 2024. PMID: 38566222 Free PMC article. No abstract available.
Mitochondrial proteostasis mediated by CRL5 Ozz and Alix maintains skeletal muscle function.
Campos Y, Rodriguez-Enriquez R, Palacios G, Van de Vlekkert D, Qiu X, Weesner J, Gomero E, Demmers J, Bertorini T, Opferman JT, Grosveld GC, d'Azzo A. Campos Y, et al. Among authors: opferman jt. bioRxiv [Preprint]. 2023 Jul 11:2023.07.11.548601. doi: 10.1101/2023.07.11.548601. bioRxiv. 2023. PMID: 37503076 Free PMC article. Preprint.
Apoptotic cell death in disease-Current understanding of the NCCD 2023.
Vitale I, Pietrocola F, Guilbaud E, Aaronson SA, Abrams JM, Adam D, Agostini M, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Aqeilan RI, Arama E, Baehrecke EH, Balachandran S, Bano D, Barlev NA, Bartek J, Bazan NG, Becker C, Bernassola F, Bertrand MJM, Bianchi ME, Blagosklonny MV, Blander JM, Blandino G, Blomgren K, Borner C, Bortner CD, Bove P, Boya P, Brenner C, Broz P, Brunner T, Damgaard RB, Calin GA, Campanella M, Candi E, Carbone M, Carmona-Gutierrez D, Cecconi F, Chan FK, Chen GQ, Chen Q, Chen YH, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Ciliberto G, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Daugaard M, Dawson TM, Dawson VL, De Maria R, De Strooper B, Debatin KM, Deberardinis RJ, Degterev A, Del Sal G, Deshmukh M, Di Virgilio F, Diederich M, Dixon SJ, Dynlacht BD, El-Deiry WS, Elrod JW, Engeland K, Fimia GM, Galassi C, Ganini C, Garcia-Saez AJ, Garg AD, Garrido C, Gavathiotis E, Gerlic M, Ghosh S, Green DR, Greene LA, Gronemeyer H, Häcker G, Hajnóczky G, Hardwick JM, Haupt Y, He S, Heery DM, Hengartner MO, Hetz C, Hildeman DA, Ichijo H, Inoue S, Jäättelä M, Janic A, Joseph B, Jost PJ, Kanneganti TD, Karin M, Kashkar H, Kaufmann T, Kelly … See abstract for full author list ➔ Vitale I, et al. Among authors: opferman jt. Cell Death Differ. 2023 May;30(5):1097-1154. doi: 10.1038/s41418-023-01153-w. Epub 2023 Apr 26. Cell Death Differ. 2023. PMID: 37100955 Free PMC article. Review.
MCL-1 is a master regulator of cancer dependency on fatty acid oxidation.
Prew MS, Adhikary U, Choi DW, Portero EP, Paulo JA, Gowda P, Budhraja A, Opferman JT, Gygi SP, Danial NN, Walensky LD. Prew MS, et al. Among authors: opferman jt. Cell Rep. 2022 Oct 4;41(1):111445. doi: 10.1016/j.celrep.2022.111445. Cell Rep. 2022. PMID: 36198266 Free PMC article.
The Role of Mcl-1 in Embryonic Neural Precursor Cell Apoptosis.
Flemmer RT, Connolly SP, Geizer BA, Opferman JT, Vanderluit JL. Flemmer RT, et al. Among authors: opferman jt. Front Cell Dev Biol. 2021 Apr 20;9:659531. doi: 10.3389/fcell.2021.659531. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33959612 Free PMC article.
90 results