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Disrupted Binding of Cystathionine γ-Lyase to p53 Promotes Endothelial Senescence.
Hu J, Leisegang MS, Looso M, Drekolia MK, Wittig J, Mettner J, Karantanou C, Kyselova A, Dumbovic G, Li X, Li Y, Guenther S, John D, Siragusa M, Zukunft S, Oo JA, Wittig I, Hille S, Weigert A, Knapp S, Brandes RP, Müller OJ, Papapetropoulos A, Sigala F, Dobreva G, Kojonazarov B, Fleming I, Bibli SI. Hu J, et al. Among authors: oo ja. Circ Res. 2023 Oct 27;133(10):842-857. doi: 10.1161/CIRCRESAHA.123.323084. Epub 2023 Oct 6. Circ Res. 2023. PMID: 37800327
The endothelial-enriched lncRNA LINC00607 mediates angiogenic function.
Boos F, Oo JA, Warwick T, Günther S, Izquierdo Ponce J, Lopez M, Rafii D, Buchmann G, Pham MD, Msheik ZS, Li T, Seredinski S, Haydar S, Kashefiolasl S, Plate KH, Behr R, Mietsch M, Krishnan J, Pullamsetti SS, Bibli SI, Hinkel R, Baker AH, Boon RA, Schulz MH, Wittig I, Miller FJ Jr, Brandes RP, Leisegang MS. Boos F, et al. Among authors: oo ja. Basic Res Cardiol. 2023 Jan 26;118(1):5. doi: 10.1007/s00395-023-00978-3. Basic Res Cardiol. 2023. PMID: 36700983 Free PMC article.
Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2.
Oo JA, Pálfi K, Warwick T, Wittig I, Prieto-Garcia C, Matkovic V, Tomašković I, Boos F, Izquierdo Ponce J, Teichmann T, Petriukov K, Haydar S, Maegdefessel L, Wu Z, Pham MD, Krishnan J, Baker AH, Günther S, Ulrich HD, Dikic I, Leisegang MS, Brandes RP. Oo JA, et al. Cell Rep. 2022 Nov 15;41(7):111670. doi: 10.1016/j.celrep.2022.111670. Cell Rep. 2022. PMID: 36384122 Free PMC article.
HIF1α-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex.
Leisegang MS, Bains JK, Seredinski S, Oo JA, Krause NM, Kuo CC, Günther S, Sentürk Cetin N, Warwick T, Cao C, Boos F, Izquierdo Ponce J, Haydar S, Bednarz R, Valasarajan C, Fuhrmann DC, Preussner J, Looso M, Pullamsetti SS, Schulz MH, Jonker HRA, Richter C, Rezende F, Gilsbach R, Pflüger-Müller B, Wittig I, Grummt I, Ribarska T, Costa IG, Schwalbe H, Brandes RP. Leisegang MS, et al. Among authors: oo ja. Nat Commun. 2022 Nov 2;13(1):6563. doi: 10.1038/s41467-022-34252-2. Nat Commun. 2022. PMID: 36323673 Free PMC article.
DNA topoisomerase inhibition with the HIF inhibitor acriflavine promotes transcription of lncRNAs in endothelial cells.
Seredinski S, Boos F, Günther S, Oo JA, Warwick T, Izquierdo Ponce J, Lillich FF, Proschak E, Knapp S, Gilsbach R, Pflüger-Müller B, Brandes RP, Leisegang MS. Seredinski S, et al. Among authors: oo ja. Mol Ther Nucleic Acids. 2022 Jan 25;27:1023-1035. doi: 10.1016/j.omtn.2022.01.016. eCollection 2022 Mar 8. Mol Ther Nucleic Acids. 2022. PMID: 35228897 Free PMC article.
The endocannabinoid anandamide has an anti-inflammatory effect on CCL2 expression in vascular smooth muscle cells.
Pflüger-Müller B, Oo JA, Heering J, Warwick T, Proschak E, Günther S, Looso M, Rezende F, Fork C, Geisslinger G, Thomas D, Gurke R, Steinhilber D, Schulz M, Leisegang MS, Brandes RP. Pflüger-Müller B, et al. Among authors: oo ja. Basic Res Cardiol. 2020 Apr 22;115(3):34. doi: 10.1007/s00395-020-0793-3. Basic Res Cardiol. 2020. PMID: 32323032 Free PMC article.
16 results