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Page 1
Saracatinib, a Selective Src Kinase Inhibitor, Blocks Fibrotic Responses in Preclinical Models of Pulmonary Fibrosis.
Ahangari F, Becker C, Foster DG, Chioccioli M, Nelson M, Beke K, Wang X, Justet A, Adams T, Readhead B, Meador C, Correll K, Lili LN, Roybal HM, Rose KA, Ding S, Barnthaler T, Briones N, DeIuliis G, Schupp JC, Li Q, Omote N, Aschner Y, Sharma L, Kopf KW, Magnusson B, Hicks R, Backmark A, Dela Cruz CS, Rosas I, Cousens LP, Dudley JT, Kaminski N, Downey GP. Ahangari F, et al. Among authors: omote n. Am J Respir Crit Care Med. 2022 Dec 15;206(12):1463-1479. doi: 10.1164/rccm.202010-3832OC. Am J Respir Crit Care Med. 2022. PMID: 35998281 Free PMC article.
Integrated Single-Cell Atlas of Endothelial Cells of the Human Lung.
Schupp JC, Adams TS, Cosme C Jr, Raredon MSB, Yuan Y, Omote N, Poli S, Chioccioli M, Rose KA, Manning EP, Sauler M, DeIuliis G, Ahangari F, Neumark N, Habermann AC, Gutierrez AJ, Bui LT, Lafyatis R, Pierce RW, Meyer KB, Nawijn MC, Teichmann SA, Banovich NE, Kropski JA, Niklason LE, Pe'er D, Yan X, Homer RJ, Rosas IO, Kaminski N. Schupp JC, et al. Among authors: omote n. Circulation. 2021 Jul 27;144(4):286-302. doi: 10.1161/CIRCULATIONAHA.120.052318. Epub 2021 May 25. Circulation. 2021. PMID: 34030460 Free PMC article.
Fibroblasts positive for meflin have anti-fibrotic properties in pulmonary fibrosis.
Nakahara Y, Hashimoto N, Sakamoto K, Enomoto A, Adams TS, Yokoi T, Omote N, Poli S, Ando A, Wakahara K, Suzuki A, Inoue M, Hara A, Mizutani Y, Imaizumi K, Kawabe T, Rosas IO, Takahashi M, Kaminski N, Hasegawa Y. Nakahara Y, et al. Among authors: omote n. Eur Respir J. 2021 Dec 23;58(6):2003397. doi: 10.1183/13993003.03397-2020. Print 2021 Dec. Eur Respir J. 2021. PMID: 34049947 Free article.
Characterization of the COPD alveolar niche using single-cell RNA sequencing.
Sauler M, McDonough JE, Adams TS, Kothapalli N, Barnthaler T, Werder RB, Schupp JC, Nouws J, Robertson MJ, Coarfa C, Yang T, Chioccioli M, Omote N, Cosme C Jr, Poli S, Ayaub EA, Chu SG, Jensen KH, Gomez JL, Britto CJ, Raredon MSB, Niklason LE, Wilson AA, Timshel PN, Kaminski N, Rosas IO. Sauler M, et al. Among authors: omote n. Nat Commun. 2022 Jan 25;13(1):494. doi: 10.1038/s41467-022-28062-9. Nat Commun. 2022. PMID: 35078977 Free PMC article.
BMP3b Is a Novel Antifibrotic Molecule Regulated by Meflin in Lung Fibroblasts.
Suzuki A, Sakamoto K, Nakahara Y, Enomoto A, Hino J, Ando A, Inoue M, Shiraki Y, Omote N, Kusaka M, Fukihara J, Hashimoto N. Suzuki A, et al. Among authors: omote n. Am J Respir Cell Mol Biol. 2022 Oct;67(4):446-458. doi: 10.1165/rcmb.2021-0484OC. Am J Respir Cell Mol Biol. 2022. PMID: 35728045
Direct regulation of transforming growth factor β-induced epithelial-mesenchymal transition by the protein phosphatase activity of unphosphorylated PTEN in lung cancer cells.
Kusunose M, Hashimoto N, Kimura M, Ogata R, Aoyama D, Sakamoto K, Miyazaki S, Ando A, Omote N, Imaizumi K, Kawabe T, Hasegawa Y. Kusunose M, et al. Among authors: omote n. Cancer Sci. 2015 Dec;106(12):1693-704. doi: 10.1111/cas.12831. Epub 2015 Nov 6. Cancer Sci. 2015. PMID: 26450531 Free PMC article.
Hypoxia-induced modulation of PTEN activity and EMT phenotypes in lung cancers.
Kohnoh T, Hashimoto N, Ando A, Sakamoto K, Miyazaki S, Aoyama D, Kusunose M, Kimura M, Omote N, Imaizumi K, Kawabe T, Hasegawa Y. Kohnoh T, et al. Among authors: omote n. Cancer Cell Int. 2016 Apr 18;16:33. doi: 10.1186/s12935-016-0308-3. eCollection 2016. Cancer Cell Int. 2016. PMID: 27095949 Free PMC article.
30 results