Olsen PA - Search Results

1

The Tankyrase Inhibitor OM-153 Demonstrates Antitumor Efficacy and a Therapeutic Window in Mouse Models.

Brinch SA, Amundsen-Isaksen E, Espada S, Hammarström C, Aizenshtadt A, Olsen PA, Holmen L, Høyem M, Scholz H, Grødeland G, Sowa ST, Galera-Prat A, Lehtiö L, Meerts IATM, Leenders RGG, Wegert A, Krauss S, Waaler J. Brinch SA, et al. Among authors: olsen pa. Cancer Res Commun. 2022 Apr 20;2(4):233-245. doi: 10.1158/2767-9764.CRC-22-0027. eCollection 2022 Apr. Cancer Res Commun. 2022. PMID: 36873622 Free PMC article.

2

Branched oligonucleotides induce in vivo gene conversion of a mutated EGFP reporter.

Olsen PA, McKeen C, Krauss S. Olsen PA, et al. Gene Ther. 2003 Oct;10(21):1830-40. doi: 10.1038/sj.gt.3302079. Gene Ther. 2003. PMID: 12960973

3

Implications of cell cycle progression on functional sequence correction by short single-stranded DNA oligonucleotides.

Olsen PA, Randol M, Krauss S. Olsen PA, et al. Gene Ther. 2005 Mar;12(6):546-51. doi: 10.1038/sj.gt.3302454. Gene Ther. 2005. PMID: 15674399

4

Genomic sequence correction by single-stranded DNA oligonucleotides: role of DNA synthesis and chemical modifications of the oligonucleotide ends.

Olsen PA, Randøl M, Luna L, Brown T, Krauss S. Olsen PA, et al. J Gene Med. 2005 Dec;7(12):1534-44. doi: 10.1002/jgm.804. J Gene Med. 2005. PMID: 16025558

5

Cellular responses to targeted genomic sequence modification using single-stranded oligonucleotides and zinc-finger nucleases.

Olsen PA, Solhaug A, Booth JA, Gelazauskaite M, Krauss S. Olsen PA, et al. DNA Repair (Amst). 2009 Mar 1;8(3):298-308. doi: 10.1016/j.dnarep.2008.11.011. Epub 2008 Dec 30. DNA Repair (Amst). 2009. PMID: 19071233

6

Analysis of illegitimate genomic integration mediated by zinc-finger nucleases: implications for specificity of targeted gene correction.

Olsen PA, Gelazauskaite M, Randøl M, Krauss S. Olsen PA, et al. BMC Mol Biol. 2010 May 10;11:35. doi: 10.1186/1471-2199-11-35. BMC Mol Biol. 2010. PMID: 20459736 Free PMC article.

7

Implications of targeted genomic disruption of β-catenin in BxPC-3 pancreatic adenocarcinoma cells.

Olsen PA, Solberg NT, Lund K, Vehus T, Gelazauskaite M, Wilson SR, Krauss S. Olsen PA, et al. PLoS One. 2014 Dec 23;9(12):e115496. doi: 10.1371/journal.pone.0115496. eCollection 2014. PLoS One. 2014. PMID: 25536063 Free PMC article.

8

Expression profiling of wild type and β-catenin gene disrupted human BxPC-3 pancreatic adenocarcinoma cells.

Olsen PA, Lund K, Krauss S. Olsen PA, et al. Genom Data. 2015 Apr 15;4:150-2. doi: 10.1016/j.gdata.2015.04.010. eCollection 2015 Jun. Genom Data. 2015. PMID: 26484203 Free PMC article.

9

Discovery of a Novel Series of Tankyrase Inhibitors by a Hybridization Approach.

Anumala UR, Waaler J, Nkizinkiko Y, Ignatev A, Lazarow K, Lindemann P, Olsen PA, Murthy S, Obaji E, Majouga AG, Leonov S, von Kries JP, Lehtiö L, Krauss S, Nazaré M. Anumala UR, et al. Among authors: olsen pa. J Med Chem. 2017 Dec 28;60(24):10013-10025. doi: 10.1021/acs.jmedchem.7b00883. Epub 2017 Dec 8. J Med Chem. 2017. PMID: 29155568

10

TANKYRASE Inhibition Enhances the Antiproliferative Effect of PI3K and EGFR Inhibition, Mutually Affecting β-CATENIN and AKT Signaling in Colorectal Cancer.

Solberg NT, Waaler J, Lund K, Mygland L, Olsen PA, Krauss S. Solberg NT, et al. Among authors: olsen pa. Mol Cancer Res. 2018 Mar;16(3):543-553. doi: 10.1158/1541-7786.MCR-17-0362. Epub 2017 Dec 8. Mol Cancer Res. 2018. PMID: 29222171

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