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CCR8-targeted specific depletion of clonally expanded Treg cells in tumor tissues evokes potent tumor immunity with long-lasting memory.
Kidani Y, Nogami W, Yasumizu Y, Kawashima A, Tanaka A, Sonoda Y, Tona Y, Nashiki K, Matsumoto R, Hagiwara M, Osaki M, Dohi K, Kanazawa T, Ueyama A, Yoshikawa M, Yoshida T, Matsumoto M, Hojo K, Shinonome S, Yoshida H, Hirata M, Haruna M, Nakamura Y, Motooka D, Okuzaki D, Sugiyama Y, Kinoshita M, Okuno T, Kato T, Hatano K, Uemura M, Imamura R, Yokoi K, Tanemura A, Shintani Y, Kimura T, Nonomura N, Wada H, Mori M, Doki Y, Ohkura N, Sakaguchi S. Kidani Y, et al. Among authors: okuno t. Proc Natl Acad Sci U S A. 2022 Feb 15;119(7):e2114282119. doi: 10.1073/pnas.2114282119. Proc Natl Acad Sci U S A. 2022. PMID: 35140181 Free PMC article.
Lamtor1 Is Critically Required for CD4+ T Cell Proliferation and Regulatory T Cell Suppressive Function.
Hosokawa T, Kimura T, Nada S, Okuno T, Ito D, Kang S, Nojima S, Yamashita K, Nakatani T, Hayama Y, Kato Y, Kinehara Y, Nishide M, Mikami N, Koyama S, Takamatsu H, Okuzaki D, Ohkura N, Sakaguchi S, Okada M, Kumanogoh A. Hosokawa T, et al. Among authors: okuno t. J Immunol. 2017 Sep 15;199(6):2008-2019. doi: 10.4049/jimmunol.1700157. Epub 2017 Aug 2. J Immunol. 2017. PMID: 28768723
Antigen specific B cells in myasthenia gravis patients.
Takata K, Kinoshita M, Mochizuki H, Okuno T. Takata K, et al. Among authors: okuno t. Immunol Med. 2020 Jun;43(2):65-71. doi: 10.1080/25785826.2020.1724756. Epub 2020 Feb 11. Immunol Med. 2020. PMID: 32046601 Review.
A Metagenome-Wide Association Study of Gut Microbiome in Patients With Multiple Sclerosis Revealed Novel Disease Pathology.
Kishikawa T, Ogawa K, Motooka D, Hosokawa A, Kinoshita M, Suzuki K, Yamamoto K, Masuda T, Matsumoto Y, Nii T, Maeda Y, Nakamura S, Inohara H, Mochizuki H, Okuno T, Okada Y. Kishikawa T, et al. Among authors: okuno t. Front Cell Infect Microbiol. 2020 Dec 11;10:585973. doi: 10.3389/fcimb.2020.585973. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 33363050 Free PMC article.
Anti-AQP4 autoantibodies promote ATP release from astrocytes and induce mechanical pain in rats.
Ishikura T, Kinoshita M, Shimizu M, Yasumizu Y, Motooka D, Okuzaki D, Yamashita K, Murata H, Beppu S, Koda T, Tada S, Shiraishi N, Sugiyama Y, Miyamoto K, Kusunoki S, Sugimoto T, Kumanogoh A, Okuno T, Mochizuki H. Ishikura T, et al. Among authors: okuno t. J Neuroinflammation. 2021 Aug 21;18(1):181. doi: 10.1186/s12974-021-02232-w. J Neuroinflammation. 2021. PMID: 34419102 Free PMC article.
1,486 results