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YAP-dependent necrosis occurs in early stages of Alzheimer's disease and regulates mouse model pathology.
Tanaka H, Homma H, Fujita K, Kondo K, Yamada S, Jin X, Waragai M, Ohtomo G, Iwata A, Tagawa K, Atsuta N, Katsuno M, Tomita N, Furukawa K, Saito Y, Saito T, Ichise A, Shibata S, Arai H, Saido T, Sudol M, Muramatsu SI, Okano H, Mufson EJ, Sobue G, Murayama S, Okazawa H. Tanaka H, et al. Among authors: okazawa h. Nat Commun. 2020 Jan 24;11(1):507. doi: 10.1038/s41467-020-14353-6. Nat Commun. 2020. PMID: 31980612 Free PMC article.
trk immunoreactivity at neuronal dendrite and cell body.
Okazawa H, Nishiyama K, Kamei M, Washizaki K, Murayama S, Kwak S, Kanazawa I. Okazawa H, et al. Biochem Biophys Res Commun. 1993 Jul 30;194(2):683-90. doi: 10.1006/bbrc.1993.1876. Biochem Biophys Res Commun. 1993. PMID: 8343154
Presenilin 1 binds to amyloid precursor protein directly.
Waragai M, Imafuku I, Takeuchi S, Kanazawa I, Oyama F, Udagawa Y, Kawabata M, Okazawa H. Waragai M, et al. Among authors: okazawa h. Biochem Biophys Res Commun. 1997 Oct 20;239(2):480-2. doi: 10.1006/bbrc.1997.7488. Biochem Biophys Res Commun. 1997. PMID: 9344855
Polar amino acid-rich sequences bind to polyglutamine tracts.
Imafuku I, Waragai M, Takeuchi S, Kanazawa I, Kawabata M, Mouradian MM, Okazawa H. Imafuku I, et al. Among authors: okazawa h. Biochem Biophys Res Commun. 1998 Dec 9;253(1):16-20. doi: 10.1006/bbrc.1998.9725. Biochem Biophys Res Commun. 1998. PMID: 9875212
JNK activation is associated with intracellular beta-amyloid accumulation.
Shoji M, Iwakami N, Takeuchi S, Waragai M, Suzuki M, Kanazawa I, Lippa CF, Ono S, Okazawa H. Shoji M, et al. Among authors: okazawa h. Brain Res Mol Brain Res. 2000 Dec 28;85(1-2):221-33. doi: 10.1016/s0169-328x(00)00245-x. Brain Res Mol Brain Res. 2000. PMID: 11146125
512 results