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An inhaled ACE2 decoy confers protection against SARS-CoV-2 infection in preclinical models.
Urano E, Itoh Y, Suzuki T, Sasaki T, Kishikawa JI, Akamatsu K, Higuchi Y, Sakai Y, Okamura T, Mitoma S, Sugihara F, Takada A, Kimura M, Nakao S, Hirose M, Sasaki T, Koketsu R, Tsuji S, Yanagida S, Shioda T, Hara E, Matoba S, Matsuura Y, Kanda Y, Arase H, Okada M, Takagi J, Kato T, Hoshino A, Yasutomi Y, Saito A, Okamoto T. Urano E, et al. Among authors: okamura t. Sci Transl Med. 2023 Aug 30;15(711):eadi2623. doi: 10.1126/scitranslmed.adi2623. Epub 2023 Aug 30. Sci Transl Med. 2023. PMID: 37647387
Recombinant Ag85B vaccine by taking advantage of characteristics of human parainfluenza type 2 virus vector showed Mycobacteria-specific immune responses by intranasal immunization.
Watanabe K, Matsubara A, Kawano M, Mizuno S, Okamura T, Tsujimura Y, Inada H, Nosaka T, Matsuo K, Yasutomi Y. Watanabe K, et al. Among authors: okamura t. Vaccine. 2014 Mar 26;32(15):1727-35. doi: 10.1016/j.vaccine.2013.11.108. Epub 2014 Jan 29. Vaccine. 2014. PMID: 24486310
Protective Immune Responses Elicited by Deglycosylated Live-Attenuated Simian Immunodeficiency Virus Vaccine Are Associated with IL-15 Effector Functions.
Watanabe S, Fujino M, Saito Y, Ahmed N, Sato H, Sugimoto C, Okamura T, Hanaki K, Nakayama EE, Shioda T, Matsushima K, Ansari AA, Villinger F, Mori K. Watanabe S, et al. Among authors: okamura t. J Immunol. 2020 Sep 1;205(5):1331-1344. doi: 10.4049/jimmunol.1901431. Epub 2020 Aug 3. J Immunol. 2020. PMID: 32747501 Free PMC article.
CD8 T Cells Show Protection against Highly Pathogenic Simian Immunodeficiency Virus (SIV) after Vaccination with SIV Gene-Expressing BCG Prime and Vaccinia Virus/Sendai Virus Vector Boosts.
Kato S, Shida H, Okamura T, Zhang X, Miura T, Mukai T, Inoue M, Shu T, Naruse TK, Kimura A, Yasutomi Y, Matsuo K. Kato S, et al. Among authors: okamura t. J Virol. 2021 Jan 28;95(4):e01718-20. doi: 10.1128/JVI.01718-20. Print 2021 Jan 28. J Virol. 2021. PMID: 33087465 Free PMC article.
Vaccination with Intradermal Bacillus Calmette-Guérin Provides Robust Protection against Extrapulmonary Tuberculosis but Not Pulmonary Infection in Cynomolgus Macaques.
Tsujimura Y, Shiogama Y, Soma S, Okamura T, Takano J, Urano E, Murakata Y, Kawano A, Yamakawa N, Asaka MN, Matsuo K, Yasutomi Y. Tsujimura Y, et al. Among authors: okamura t. J Immunol. 2020 Dec 1;205(11):3023-3036. doi: 10.4049/jimmunol.2000386. Epub 2020 Oct 23. J Immunol. 2020. PMID: 33097574
COVID-19 cynomolgus macaque model reflecting human COVID-19 pathological conditions.
Urano E, Okamura T, Ono C, Ueno S, Nagata S, Kamada H, Higuchi M, Furukawa M, Kamitani W, Matsuura Y, Kawaoka Y, Yasutomi Y. Urano E, et al. Among authors: okamura t. Proc Natl Acad Sci U S A. 2021 Oct 26;118(43):e2104847118. doi: 10.1073/pnas.2104847118. Proc Natl Acad Sci U S A. 2021. PMID: 34625475 Free PMC article.
2,834 results