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Anti-nucleocapsid antibodies enhance the production of IL-6 induced by SARS-CoV-2 N protein.
Nakayama EE, Kubota-Koketsu R, Sasaki T, Suzuki K, Uno K, Shimizu J, Okamoto T, Matsumoto H, Matsuura H, Hashimoto S, Tanaka T, Harada H, Tomita M, Kaneko M, Yoshizaki K, Shioda T. Nakayama EE, et al. Among authors: okamoto t. Sci Rep. 2022 May 16;12(1):8108. doi: 10.1038/s41598-022-12252-y. Sci Rep. 2022. PMID: 35577892 Free PMC article.
An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies.
Liu Y, Soh WT, Kishikawa JI, Hirose M, Nakayama EE, Li S, Sasai M, Suzuki T, Tada A, Arakawa A, Matsuoka S, Akamatsu K, Matsuda M, Ono C, Torii S, Kishida K, Jin H, Nakai W, Arase N, Nakagawa A, Matsumoto M, Nakazaki Y, Shindo Y, Kohyama M, Tomii K, Ohmura K, Ohshima S, Okamoto T, Yamamoto M, Nakagami H, Matsuura Y, Nakagawa A, Kato T, Okada M, Standley DM, Shioda T, Arase H. Liu Y, et al. Among authors: okamoto t. Cell. 2021 Jun 24;184(13):3452-3466.e18. doi: 10.1016/j.cell.2021.05.032. Epub 2021 May 24. Cell. 2021. PMID: 34139176 Free PMC article.
Cell response analysis in SARS-CoV-2 infected bronchial organoids.
Sano E, Suzuki T, Hashimoto R, Itoh Y, Sakamoto A, Sakai Y, Saito A, Okuzaki D, Motooka D, Muramoto Y, Noda T, Takasaki T, Sakuragi JI, Minami S, Kobayashi T, Yamamoto T, Matsumura Y, Nagao M, Okamoto T, Takayama K. Sano E, et al. Among authors: okamoto t. Commun Biol. 2022 May 30;5(1):516. doi: 10.1038/s42003-022-03499-2. Commun Biol. 2022. PMID: 35637255 Free PMC article.
Antibody feedback contributes to facilitating the development of Omicron-reactive memory B cells in SARS-CoV-2 mRNA vaccinees.
Inoue T, Shinnakasu R, Kawai C, Yamamoto H, Sakakibara S, Ono C, Itoh Y, Terooatea T, Yamashita K, Okamoto T, Hashii N, Ishii-Watabe A, Butler NS, Matsuura Y, Matsumoto H, Otsuka S, Hiraoka K, Teshima T, Murakami M, Kurosaki T. Inoue T, et al. Among authors: okamoto t. J Exp Med. 2023 Feb 6;220(2):e20221786. doi: 10.1084/jem.20221786. Epub 2022 Dec 13. J Exp Med. 2023. PMID: 36512034 Free PMC article.
Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2.
Higuchi Y, Suzuki T, Arimori T, Ikemura N, Mihara E, Kirita Y, Ohgitani E, Mazda O, Motooka D, Nakamura S, Sakai Y, Itoh Y, Sugihara F, Matsuura Y, Matoba S, Okamoto T, Takagi J, Hoshino A. Higuchi Y, et al. Among authors: okamoto t. Nat Commun. 2021 Jun 21;12(1):3802. doi: 10.1038/s41467-021-24013-y. Nat Commun. 2021. PMID: 34155214 Free PMC article.
An engineered ACE2 decoy neutralizes the SARS-CoV-2 Omicron variant and confers protection against infection in vivo.
Ikemura N, Taminishi S, Inaba T, Arimori T, Motooka D, Katoh K, Kirita Y, Higuchi Y, Li S, Suzuki T, Itoh Y, Ozaki Y, Nakamura S, Matoba S, Standley DM, Okamoto T, Takagi J, Hoshino A. Ikemura N, et al. Among authors: okamoto t. Sci Transl Med. 2022 Jun 22;14(650):eabn7737. doi: 10.1126/scitranslmed.abn7737. Epub 2022 Jun 22. Sci Transl Med. 2022. PMID: 35471044 Free PMC article.
4,074 results