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Phase 1/2a clinical trial in ALS with ropinirole, a drug candidate identified by iPSC drug discovery.
Morimoto S, Takahashi S, Ito D, Daté Y, Okada K, Kato C, Nakamura S, Ozawa F, Chyi CM, Nishiyama A, Suzuki N, Fujimori K, Kondo T, Takao M, Hirai M, Kabe Y, Suematsu M, Jinzaki M, Aoki M, Fujiki Y, Sato Y, Suzuki N, Nakahara J; Pooled Resource Open-Access ALS Clinical Trials Consortium; Okano H. Morimoto S, et al. Among authors: okada k. Cell Stem Cell. 2023 Jun 1;30(6):766-780.e9. doi: 10.1016/j.stem.2023.04.017. Cell Stem Cell. 2023. PMID: 37267913 Free article. Clinical Trial.
Evaluation of [18F]PI-2620, a second-generation selective tau tracer, for assessing four-repeat tauopathies.
Tezuka T, Takahata K, Seki M, Tabuchi H, Momota Y, Shiraiwa M, Suzuki N, Morimoto A, Nakahara T, Iwabuchi Y, Miura E, Yamamoto Y, Sano Y, Funaki K, Yamagata B, Ueda R, Yoshizaki T, Mashima K, Shibata M, Oyama M, Okada K, Kubota M, Okita H, Takao M, Jinzaki M, Nakahara J, Mimura M, Ito D. Tezuka T, et al. Among authors: okada k. Brain Commun. 2021 Aug 24;3(4):fcab190. doi: 10.1093/braincomms/fcab190. eCollection 2021. Brain Commun. 2021. PMID: 34632382 Free PMC article.
Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS.
Miller TM, Cudkowicz ME, Genge A, Shaw PJ, Sobue G, Bucelli RC, Chiò A, Van Damme P, Ludolph AC, Glass JD, Andrews JA, Babu S, Benatar M, McDermott CJ, Cochrane T, Chary S, Chew S, Zhu H, Wu F, Nestorov I, Graham D, Sun P, McNeill M, Fanning L, Ferguson TA, Fradette S; VALOR and OLE Working Group. Miller TM, et al. N Engl J Med. 2022 Sep 22;387(12):1099-1110. doi: 10.1056/NEJMoa2204705. N Engl J Med. 2022. PMID: 36129998 Free article. Clinical Trial.
Phenotypic Insights Into Anti-IgLON5 Disease in IgLON5-Deficient Mice.
Lee SY, Shoji H, Shimozawa A, Aoyagi H, Sato Y, Tsumagari K, Terumitsu M, Motegi H, Okada K, Sekiguchi K, Kuromitsu J, Nakahara J, Miyakawa T, Ito D. Lee SY, et al. Among authors: okada k. Neurol Neuroimmunol Neuroinflamm. 2024 May;11(3):e200234. doi: 10.1212/NXI.0000000000200234. Epub 2024 Apr 24. Neurol Neuroimmunol Neuroinflamm. 2024. PMID: 38657185 Free PMC article.
Suitable indications of eculizumab for patients with refractory generalized myasthenia gravis.
Oyama M, Okada K, Masuda M, Shimizu Y, Yokoyama K, Uzawa A, Kawaguchi N, Ikeguchi R, Hoshino Y, Hatano T, Ozawa Y, Nakahara J, Aizawa H, Kitagawa K, Hattori N, Kuwabara S, Murai H, Suzuki S. Oyama M, et al. Among authors: okada k. Ther Adv Neurol Disord. 2020 Mar 18;13:1756286420904207. doi: 10.1177/1756286420904207. eCollection 2020. Ther Adv Neurol Disord. 2020. PMID: 32215054 Free PMC article.
5,889 results