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Toso controls encephalitogenic immune responses by dendritic cells and regulatory T cells.
Brenner D, Brüstle A, Lin GH, Lang PA, Duncan GS, Knobbe-Thomsen CB, St Paul M, Reardon C, Tusche MW, Snow B, Hamilton SR, Pfefferle A, Gilani SO, Ohashi PS, Lang KS, Mak TW. Brenner D, et al. Among authors: ohashi ps. Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1060-5. doi: 10.1073/pnas.1323166111. Epub 2014 Jan 7. Proc Natl Acad Sci U S A. 2014. PMID: 24398517 Free PMC article.
B7-H4 expression by nonhematopoietic cells in the tumor microenvironment promotes antitumor immunity.
Rahbar R, Lin A, Ghazarian M, Yau HL, Paramathas S, Lang PA, Schildknecht A, Elford AR, Garcia-Batres C, Martin B, Berman HK, Leong WL, McCready DR, Reedijk M, Done SJ, Miller N, Youngson B, Suh WK, Mak TW, Ohashi PS. Rahbar R, et al. Among authors: ohashi ps. Cancer Immunol Res. 2015 Feb;3(2):184-95. doi: 10.1158/2326-6066.CIR-14-0113. Epub 2014 Dec 19. Cancer Immunol Res. 2015. PMID: 25527357
Zeroing in on Tumor-Reactive TILs.
Ohashi PS. Ohashi PS. Cancer Immunol Res. 2016 Sep 2;4(9):719. doi: 10.1158/2326-6066.CIR-16-0179. Cancer Immunol Res. 2016. PMID: 27590279
K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression.
Hao Z, Sheng Y, Duncan GS, Li WY, Dominguez C, Sylvester J, Su YW, Lin GH, Snow BE, Brenner D, You-Ten A, Haight J, Inoue S, Wakeham A, Elford A, Hamilton S, Liang Y, Zúñiga-Pflücker JC, He HH, Ohashi PS, Mak TW. Hao Z, et al. Among authors: ohashi ps. Nat Commun. 2017 Jan 13;8:14003. doi: 10.1038/ncomms14003. Nat Commun. 2017. PMID: 28084302 Free PMC article.
A distinct innate lymphoid cell population regulates tumor-associated T cells.
Crome SQ, Nguyen LT, Lopez-Verges S, Yang SY, Martin B, Yam JY, Johnson DJ, Nie J, Pniak M, Yen PH, Milea A, Sowamber R, Katz SR, Bernardini MQ, Clarke BA, Shaw PA, Lang PA, Berman HK, Pugh TJ, Lanier LL, Ohashi PS. Crome SQ, et al. Among authors: ohashi ps. Nat Med. 2017 Mar;23(3):368-375. doi: 10.1038/nm.4278. Epub 2017 Feb 6. Nat Med. 2017. PMID: 28165478 Free PMC article.
Costimulation, a surprising connection for immunotherapy.
Clouthier DL, Ohashi PS. Clouthier DL, et al. Among authors: ohashi ps. Science. 2017 Mar 31;355(6332):1373-1374. doi: 10.1126/science.aan1467. Science. 2017. PMID: 28360282 No abstract available.
Regulatory T Cells in Ovarian Cancer Are Characterized by a Highly Activated Phenotype Distinct from that in Melanoma.
Toker A, Nguyen LT, Stone SC, Yang SYC, Katz SR, Shaw PA, Clarke BA, Ghazarian D, Al-Habeeb A, Easson A, Leong WL, McCready DR, Reedijk M, Guidos CJ, Pugh TJ, Bernardini MQ, Ohashi PS. Toker A, et al. Among authors: ohashi ps. Clin Cancer Res. 2018 Nov 15;24(22):5685-5696. doi: 10.1158/1078-0432.CCR-18-0554. Epub 2018 Jul 31. Clin Cancer Res. 2018. PMID: 30065096
312 results