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Botulinum toxin type a (150 kDa) decreases exaggerated neurotransmitter release from trigeminal ganglion neurons and relieves neuropathy behaviors induced by infraorbital nerve constriction.
Kitamura Y, Matsuka Y, Spigelman I, Ishihara Y, Yamamoto Y, Sonoyama W, Kamioka H, Yamashiro T, Kuboki T, Oguma K. Kitamura Y, et al. Among authors: oguma k. Neuroscience. 2009 Apr 10;159(4):1422-9. doi: 10.1016/j.neuroscience.2009.01.066. Epub 2009 Feb 3. Neuroscience. 2009. PMID: 19409226
Intradermal injection of Botulinum toxin type A alleviates infraorbital nerve constriction-induced thermal hyperalgesia in an operant assay.
Kumada A, Matsuka Y, Spigelman I, Maruhama K, Yamamoto Y, Neubert JK, Nolan TA, Watanabe K, Maekawa K, Kamioka H, Yamashiro T, Kuboki T, Oguma K. Kumada A, et al. Among authors: oguma k. J Oral Rehabil. 2012 Jan;39(1):63-72. doi: 10.1111/j.1365-2842.2011.02236.x. Epub 2011 Jul 27. J Oral Rehabil. 2012. PMID: 21793870
Application of purified botulinum type a neurotoxin to treat experimental trigeminal neuropathy in rats and patients with urinary incontinence and prostatic hyperplasia.
Matsuka Y, Yokoyama T, Yamamoto Y, Suzuki T, Dwi Fatmawati NN, Nishikawa A, Ohyama T, Watanabe T, Kuboki T, Nagai A, Oguma K. Matsuka Y, et al. Among authors: oguma k. J Toxicol. 2012;2012:648384. doi: 10.1155/2012/648384. Epub 2012 Jun 14. J Toxicol. 2012. PMID: 22745637 Free PMC article.
Clinical application of Clostridium botulinum type A neurotoxin purified by a simple procedure for patients with urinary incontinence caused by refractory destrusor overactivity.
Lee JC, Yokoyama T, Hwang HJ, Arimitsu H, Yamamoto Y, Kawasaki M, Takigawa T, Takeshi K, Nishikawa A, Kumon H, Oguma K. Lee JC, et al. Among authors: oguma k. FEMS Immunol Med Microbiol. 2007 Oct;51(1):201-11. doi: 10.1111/j.1574-695X.2007.00301.x. Epub 2007 Aug 10. FEMS Immunol Med Microbiol. 2007. PMID: 17692094 Free article. Clinical Trial.
391 results