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94 results

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Page 1
Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial.
Butler CC, Hobbs FDR, Gbinigie OA, Rahman NM, Hayward G, Richards DB, Dorward J, Lowe DM, Standing JF, Breuer J, Khoo S, Petrou S, Hood K, Nguyen-Van-Tam JS, Patel MG, Saville BR, Marion J, Ogburn E, Allen J, Rutter H, Francis N, Thomas NPB, Evans P, Dobson M, Madden TA, Holmes J, Harris V, Png ME, Lown M, van Hecke O, Detry MA, Saunders CT, Fitzgerald M, Berry NS, Mwandigha L, Galal U, Mort S, Jani BD, Hart ND, Ahmed H, Butler D, McKenna M, Chalk J, Lavallee L, Hadley E, Cureton L, Benysek M, Andersson M, Coates M, Barrett S, Bateman C, Davies JC, Raymundo-Wood I, Ustianowski A, Carson-Stevens A, Yu LM, Little P; PANORAMIC Trial Collaborative Group. Butler CC, et al. Among authors: ogburn e. Lancet. 2023 Jan 28;401(10373):281-293. doi: 10.1016/S0140-6736(22)02597-1. Epub 2022 Dec 22. Lancet. 2023. PMID: 36566761 Free PMC article. Clinical Trial.
Telemonitoring and/or self-monitoring of blood pressure in hypertension (TASMINH4): protocol for a randomised controlled trial.
Franssen M, Farmer A, Grant S, Greenfield S, Heneghan C, Hobbs R, Hodgkinson J, Jowett S, Mant J, Martin U, Milner S, Monahan M, Ogburn E, Perera-Salazar R, Schwartz C, Yu LM, McManus RJ. Franssen M, et al. Among authors: ogburn e. BMC Cardiovasc Disord. 2017 Feb 13;17(1):58. doi: 10.1186/s12872-017-0494-5. BMC Cardiovasc Disord. 2017. PMID: 28193176 Free PMC article. Clinical Trial.
Efficacy of self-monitored blood pressure, with or without telemonitoring, for titration of antihypertensive medication (TASMINH4): an unmasked randomised controlled trial.
McManus RJ, Mant J, Franssen M, Nickless A, Schwartz C, Hodgkinson J, Bradburn P, Farmer A, Grant S, Greenfield SM, Heneghan C, Jowett S, Martin U, Milner S, Monahan M, Mort S, Ogburn E, Perera-Salazar R, Shah SA, Yu LM, Tarassenko L, Hobbs FDR; TASMINH4 investigators. McManus RJ, et al. Among authors: ogburn e. Lancet. 2018 Mar 10;391(10124):949-959. doi: 10.1016/S0140-6736(18)30309-X. Epub 2018 Feb 27. Lancet. 2018. PMID: 29499873 Free PMC article. Clinical Trial.
OPtimising Treatment for MIld Systolic hypertension in the Elderly (OPTiMISE): protocol for a randomised controlled non-inferiority trial.
Sheppard JP, Burt J, Lown M, Temple E, Benson J, Ford GA, Heneghan C, Hobbs FDR, Jowett S, Little P, Mant J, Mollison J, Nickless A, Ogburn E, Payne R, Williams M, Yu LM, McManus RJ. Sheppard JP, et al. Among authors: ogburn e. BMJ Open. 2018 Oct 4;8(9):e022930. doi: 10.1136/bmjopen-2018-022930. BMJ Open. 2018. PMID: 30287610 Free PMC article.
Primary care treatment of insomnia: study protocol for a pragmatic, multicentre, randomised controlled trial comparing nurse-delivered sleep restriction therapy to sleep hygiene (the HABIT trial).
Kyle SD, Madigan C, Begum N, Abel L, Armstrong S, Aveyard P, Bower P, Ogburn E, Siriwardena A, Yu LM, Espie CA. Kyle SD, et al. Among authors: ogburn e. BMJ Open. 2020 Mar 4;10(3):e036248. doi: 10.1136/bmjopen-2019-036248. BMJ Open. 2020. PMID: 32139496 Free PMC article.
Home and Online Management and Evaluation of Blood Pressure (HOME BP) using a digital intervention in poorly controlled hypertension: randomised controlled trial.
McManus RJ, Little P, Stuart B, Morton K, Raftery J, Kelly J, Bradbury K, Zhang J, Zhu S, Murray E, May CR, Mair FS, Michie S, Smith P, Band R, Ogburn E, Allen J, Rice C, Nuttall J, Williams B, Yardley L; HOME BP investigators. McManus RJ, et al. Among authors: ogburn e. BMJ. 2021 Jan 19;372:m4858. doi: 10.1136/bmj.m4858. BMJ. 2021. PMID: 33468518 Free PMC article. Clinical Trial.
Platform Randomised trial of INterventions against COVID-19 In older peoPLE (PRINCIPLE): protocol for a randomised, controlled, open-label, adaptive platform, trial of community treatment of COVID-19 syndromic illness in people at higher risk.
Hayward G, Butler CC, Yu LM, Saville BR, Berry N, Dorward J, Gbinigie O, van Hecke O, Ogburn E, Swayze H, Bongard E, Allen J, Tonner S, Rutter H, Tonkin-Crine S, Borek A, Judge D, Grabey J, de Lusignan S, Thomas NPB, Evans PH, Andersson MI, Llewelyn M, Patel M, Hopkins S, Hobbs FDR. Hayward G, et al. Among authors: ogburn e. BMJ Open. 2021 Jun 18;11(6):e046799. doi: 10.1136/bmjopen-2020-046799. BMJ Open. 2021. PMID: 34145016 Free PMC article.
Doxycycline for community treatment of suspected COVID-19 in people at high risk of adverse outcomes in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial.
Butler CC, Yu LM, Dorward J, Gbinigie O, Hayward G, Saville BR, Van Hecke O, Berry N, Detry MA, Saunders C, Fitzgerald M, Harris V, Djukanovic R, Gadola S, Kirkpatrick J, de Lusignan S, Ogburn E, Evans PH, Thomas NPB, Patel MG, Hobbs FDR; PRINCIPLE Trial Collaborative Group. Butler CC, et al. Among authors: ogburn e. Lancet Respir Med. 2021 Sep;9(9):1010-1020. doi: 10.1016/S2213-2600(21)00310-6. Epub 2021 Jul 27. Lancet Respir Med. 2021. PMID: 34329624 Free PMC article. Clinical Trial.
94 results