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The Wnt receptor Ryk reduces neuronal and cell survival capacity by repressing FOXO activity during the early phases of mutant huntingtin pathogenicity.
Tourette C, Farina F, Vazquez-Manrique RP, Orfila AM, Voisin J, Hernandez S, Offner N, Parker JA, Menet S, Kim J, Lyu J, Choi SH, Cormier K, Edgerly CK, Bordiuk OL, Smith K, Louise A, Halford M, Stacker S, Vert JP, Ferrante RJ, Lu W, Neri C. Tourette C, et al. Among authors: offner n. PLoS Biol. 2014 Jun 24;12(6):e1001895. doi: 10.1371/journal.pbio.1001895. eCollection 2014 Jun. PLoS Biol. 2014. PMID: 24960609 Free PMC article.
[Propagation of polyglutamine agregates in normal cells].
Offner N, Vazquez R, Néri C. Offner N, et al. Med Sci (Paris). 2009 Oct;25(10):773-4. doi: 10.1051/medsci/20092510773. Med Sci (Paris). 2009. PMID: 19849968 Free article. French. No abstract available.
Meclizine is neuroprotective in models of Huntington's disease.
Gohil VM, Offner N, Walker JA, Sheth SA, Fossale E, Gusella JF, MacDonald ME, Neri C, Mootha VK. Gohil VM, et al. Among authors: offner n. Hum Mol Genet. 2011 Jan 15;20(2):294-300. doi: 10.1093/hmg/ddq464. Epub 2010 Oct 25. Hum Mol Genet. 2011. PMID: 20977989 Free PMC article.
Trio controls the mature organization of neuronal clusters in the hindbrain.
Backer S, Hidalgo-Sánchez M, Offner N, Portales-Casamar E, Debant A, Fort P, Gauthier-Rouvière C, Bloch-Gallego E. Backer S, et al. Among authors: offner n. J Neurosci. 2007 Sep 26;27(39):10323-32. doi: 10.1523/JNEUROSCI.1102-07.2007. J Neurosci. 2007. PMID: 17898204 Free PMC article.
12 results