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Structural dynamics of the E6AP/UBE3A-E6-p53 enzyme-substrate complex.
Sailer C, Offensperger F, Julier A, Kammer KM, Walker-Gray R, Gold MG, Scheffner M, Stengel F. Sailer C, et al. Among authors: offensperger f. Nat Commun. 2018 Oct 25;9(1):4441. doi: 10.1038/s41467-018-06953-0. Nat Commun. 2018. PMID: 30361475 Free PMC article.
FAT10 and NUB1L cooperate to activate the 26S proteasome.
Brockmann F, Catone N, Wünsch C, Offensperger F, Scheffner M, Schmidtke G, Aichem A. Brockmann F, et al. Among authors: offensperger f. Life Sci Alliance. 2023 May 15;6(8):e202201463. doi: 10.26508/lsa.202201463. Print 2023 Aug. Life Sci Alliance. 2023. PMID: 37188463 Free PMC article.
A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.
Yao Z, Darowski K, St-Denis N, Wong V, Offensperger F, Villedieu A, Amin S, Malty R, Aoki H, Guo H, Xu Y, Iorio C, Kotlyar M, Emili A, Jurisica I, Neel BG, Babu M, Gingras AC, Stagljar I. Yao Z, et al. Among authors: offensperger f. Mol Cell. 2017 Jan 19;65(2):347-360. doi: 10.1016/j.molcel.2016.12.004. Epub 2017 Jan 5. Mol Cell. 2017. PMID: 28065597 Free PMC article.
Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells.
Offensperger F, Tin G, Duran-Frigola M, Hahn E, Dobner S, Ende CWA, Strohbach JW, Rukavina A, Brennsteiner V, Ogilvie K, Marella N, Kladnik K, Ciuffa R, Majmudar JD, Field SD, Bensimon A, Ferrari L, Ferrada E, Ng A, Zhang Z, Degliesposti G, Boeszoermenyi A, Martens S, Stanton R, Müller AC, Hannich JT, Hepworth D, Superti-Furga G, Kubicek S, Schenone M, Winter GE. Offensperger F, et al. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26. Science. 2024. PMID: 38662832
Peripheral priming induces plastic transcriptomic and proteomic responses in circulating neutrophils required for pathogen containment.
Kaiser R, Gold C, Joppich M, Loew Q, Akhalkatsi A, Mueller TT, Offensperger F, Droste Zu Senden A, Popp O, di Fina L, Knottenberg V, Martinez-Navarro A, Eivers L, Anjum A, Escaig R, Bruns N, Briem E, Dewender R, Muraly A, Akgöl S, Ferraro B, Hoeflinger JKL, Polewka V, Khaled NB, Allgeier J, Tiedt S, Dichgans M, Engelmann B, Enard W, Mertins P, Hubner N, Weckbach L, Zimmer R, Massberg S, Stark K, Nicolai L, Pekayvaz K. Kaiser R, et al. Among authors: offensperger f. Sci Adv. 2024 Mar 22;10(12):eadl1710. doi: 10.1126/sciadv.adl1710. Epub 2024 Mar 22. Sci Adv. 2024. PMID: 38517968 Free PMC article.
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