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Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO).
Shi Y, Cui M, Ochs K, Brendel M, Strübing FL, Briel N, Eckenweber F, Zou C, Banati RB, Liu GJ, Middleton RJ, Rupprecht R, Rudolph U, Zeilhofer HU, Rammes G, Herms J, Dorostkar MM. Shi Y, et al. Among authors: ochs k. Nat Neurosci. 2022 Mar;25(3):317-329. doi: 10.1038/s41593-022-01013-9. Epub 2022 Feb 28. Nat Neurosci. 2022. PMID: 35228700
Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation.
Biechele G, Blume T, Deussing M, Zott B, Shi Y, Xiang X, Franzmeier N, Kleinberger G, Peters F, Ochs K, Focke C, Sacher C, Wind K, Schmidt C, Lindner S, Gildehaus FJ, Eckenweber F, Beyer L, von Ungern-Sternberg B, Bartenstein P, Baumann K, Dorostkar MM, Rominger A, Cumming P, Willem M, Adelsberger H, Herms J, Brendel M. Biechele G, et al. Among authors: ochs k. Theranostics. 2021 Aug 19;11(18):8964-8976. doi: 10.7150/thno.64022. eCollection 2021. Theranostics. 2021. PMID: 34522221 Free PMC article.
Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition.
Blume T, Deussing M, Biechele G, Peters F, Zott B, Schmidt C, Franzmeier N, Wind K, Eckenweber F, Sacher C, Shi Y, Ochs K, Kleinberger G, Xiang X, Focke C, Lindner S, Gildehaus FJ, Beyer L, von Ungern-Sternberg B, Bartenstein P, Baumann K, Adelsberger H, Rominger A, Cumming P, Willem M, Dorostkar MM, Herms J, Brendel M. Blume T, et al. Among authors: ochs k. Front Aging Neurosci. 2022 Mar 30;14:854031. doi: 10.3389/fnagi.2022.854031. eCollection 2022. Front Aging Neurosci. 2022. PMID: 35431893 Free PMC article.
Correlated magnetic resonance imaging and ultramicroscopy (MR-UM) is a tool kit to assess the dynamics of glioma angiogenesis.
Breckwoldt MO, Bode J, Kurz FT, Hoffmann A, Ochs K, Ott M, Deumelandt K, Krüwel T, Schwarz D, Fischer M, Helluy X, Milford D, Kirschbaum K, Solecki G, Chiblak S, Abdollahi A, Winkler F, Wick W, Platten M, Heiland S, Bendszus M, Tews B. Breckwoldt MO, et al. Among authors: ochs k. Elife. 2016 Feb 2;5:e11712. doi: 10.7554/eLife.11712. Elife. 2016. PMID: 26830460 Free PMC article.
Microenvironmental clues for glioma immunotherapy.
Platten M, Ochs K, Lemke D, Opitz C, Wick W. Platten M, et al. Among authors: ochs k. Curr Neurol Neurosci Rep. 2014 Apr;14(4):440. doi: 10.1007/s11910-014-0440-1. Curr Neurol Neurosci Rep. 2014. PMID: 24604058 Review.
K27M-mutant histone-3 as a novel target for glioma immunotherapy.
Ochs K, Ott M, Bunse T, Sahm F, Bunse L, Deumelandt K, Sonner JK, Keil M, von Deimling A, Wick W, Platten M. Ochs K, et al. Oncoimmunology. 2017 May 12;6(7):e1328340. doi: 10.1080/2162402X.2017.1328340. eCollection 2017. Oncoimmunology. 2017. PMID: 28811969 Free PMC article.
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