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Activation of eIF4E-binding-protein-1 rescues mTORC1-induced sarcopenia by expanding lysosomal degradation capacity.
Crombie EM, Kim S, Adamson S, Dong H, Lu TC, Wu Y, Wu Y, Levy Y, Stimple N, Lam WMR, Hey HWD, Withers DJ, Hsu AL, Bay BH, Ochala J, Tsai SY. Crombie EM, et al. Among authors: ochala j. J Cachexia Sarcopenia Muscle. 2023 Feb;14(1):198-213. doi: 10.1002/jcsm.13121. Epub 2022 Nov 17. J Cachexia Sarcopenia Muscle. 2023. PMID: 36398408 Free PMC article.
CaMKK2 is not involved in contraction-stimulated AMPK activation and glucose uptake in skeletal muscle.
Negoita F, Addinsall AB, Hellberg K, Bringas CF, Hafen PS, Sermersheim TJ, Agerholm M, Lewis CTA, Ahwazi D, Ling NXY, Larsen JK, Deshmukh AS, Hossain MA, Oakhill JS, Ochala J, Brault JJ, Sankar U, Drewry DH, Scott JW, Witczak CA, Sakamoto K. Negoita F, et al. Among authors: ochala j. Mol Metab. 2023 Sep;75:101761. doi: 10.1016/j.molmet.2023.101761. Epub 2023 Jun 26. Mol Metab. 2023. PMID: 37380024 Free PMC article.
Human skeletal myopathy myosin mutations disrupt myosin head sequestration.
Carrington G, Hau A, Kosta S, Dugdale HF, Muntoni F, D'Amico A, Van den Bergh P, Romero NB, Malfatti E, Vilchez JJ, Oldfors A, Pajusalu S, Õunap K, Giralt-Pujol M, Zanoteli E, Campbell KS, Iwamoto H, Peckham M, Ochala J. Carrington G, et al. Among authors: ochala j. JCI Insight. 2023 Nov 8;8(21):e172322. doi: 10.1172/jci.insight.172322. JCI Insight. 2023. PMID: 37788100 Free PMC article.
Remodeling of skeletal muscle myosin metabolic states in hibernating mammals.
Lewis CTA, Melhedegaard EG, Ognjanovic MM, Olsen MS, Laitila J, Seaborne RAE, Gronset M, Zhang C, Iwamoto H, Hessel AL, Kuehn MN, Merino C, Amigo N, Frobert O, Giroud S, Staples JF, Goropashnaya AV, Fedorov VB, Barnes B, Toien O, Drew K, Sprenger RJ, Ochala J. Lewis CTA, et al. Among authors: ochala j. Elife. 2024 May 16;13:RP94616. doi: 10.7554/eLife.94616. Elife. 2024. PMID: 38752835 Free PMC article.
87 results