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Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment.
Elife. 2024 Mar 26;12:RP89376. doi: 10.7554/eLife.89376.
Elife. 2024.
PMID: 38529532
Free PMC article.
Effect of brain acidification on depression-related behaviors in diabetes mellitus.
Temma Y, Obi-Nagata K, Hoshiba Y, Miyake R, Katayama Y, Hagihara H, Suzuki N, Miyakawa T, Nakayama KI, Hayashi-Takagi A.
Temma Y, et al. Among authors: obi nagata k.
Front Psychiatry. 2023 Nov 29;14:1277097. doi: 10.3389/fpsyt.2023.1277097. eCollection 2023.
Front Psychiatry. 2023.
PMID: 38094594
Free PMC article.
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Distorted neurocomputation by a small number of extra-large spines in psychiatric disorders.
Obi-Nagata K, Suzuki N, Miyake R, MacDonald ML, Fish KN, Ozawa K, Nagahama K, Okimura T, Tanaka S, Kano M, Fukazawa Y, Sweet RA, Hayashi-Takagi A.
Obi-Nagata K, et al.
Sci Adv. 2023 Jun 9;9(23):eade5973. doi: 10.1126/sciadv.ade5973. Epub 2023 Jun 9.
Sci Adv. 2023.
PMID: 37294752
Free PMC article.
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Synaptic functions and their disruption in schizophrenia: From clinical evidence to synaptic optogenetics in an animal model.
Obi-Nagata K, Temma Y, Hayashi-Takagi A.
Obi-Nagata K, et al.
Proc Jpn Acad Ser B Phys Biol Sci. 2019;95(5):179-197. doi: 10.2183/pjab.95.014.
Proc Jpn Acad Ser B Phys Biol Sci. 2019.
PMID: 31080187
Free PMC article.
Review.
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