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Synthesis, cytotoxic evaluation, and molecular docking studies of novel quinazoline derivatives with benzenesulfonamide and anilide tails: Dual inhibitors of EGFR/HER2.
Alkahtani HM, Abdalla AN, Obaidullah AJ, Alanazi MM, Almehizia AA, Alanazi MG, Ahmed AY, Alwassil OI, Darwish HW, Abdel-Aziz AA, El-Azab AS. Alkahtani HM, et al. Among authors: obaidullah aj. Bioorg Chem. 2020 Jan;95:103461. doi: 10.1016/j.bioorg.2019.103461. Epub 2019 Dec 3. Bioorg Chem. 2020. PMID: 31838290
Exploring structure-activity relationship of S-substituted 2-mercaptoquinazolin-4(3H)-one including 4-ethylbenzenesulfonamides as human carbonic anhydrase inhibitors.
El-Azab AS, Abdel-Aziz AA, Ahmed HEA, Bua S, Nocentini A, AlSaif NA, Obaidullah AJ, Hefnawy MM, Supuran CT. El-Azab AS, et al. Among authors: obaidullah aj. J Enzyme Inhib Med Chem. 2020 Dec;35(1):598-609. doi: 10.1080/14756366.2020.1722121. J Enzyme Inhib Med Chem. 2020. PMID: 32009479 Free PMC article.
Synthesis, anti-inflammatory, cytotoxic, and COX-1/2 inhibitory activities of cyclic imides bearing 3-benzenesulfonamide, oxime, and β-phenylalanine scaffolds: a molecular docking study.
Abdel-Aziz AA, El-Azab AS, AlSaif NA, Alanazi MM, El-Gendy MA, Obaidullah AJ, Alkahtani HM, Almehizia AA, Al-Suwaidan IA. Abdel-Aziz AA, et al. Among authors: obaidullah aj. J Enzyme Inhib Med Chem. 2020 Dec;35(1):610-621. doi: 10.1080/14756366.2020.1722120. J Enzyme Inhib Med Chem. 2020. PMID: 32013633 Free PMC article.
Validated Microwell-Based Spectrofluorimetric Method for Quantification of Ravidasvir (New Anti-Chronic Hepatitis C Virus-GT4) in Rat Plasma and Its Application to Pharmacokinetic Study.
Hefnawy M, Al-Shehri M, Al-Rashood S, Hammad S, Alanazi M, Alsaif N, Mohammed M, Obaidullah A, El-Gendy M. Hefnawy M, et al. Drug Des Devel Ther. 2020 Oct 20;14:4377-4385. doi: 10.2147/DDDT.S237949. eCollection 2020. Drug Des Devel Ther. 2020. PMID: 33116422 Free PMC article.
Discovery of new VEGFR-2 inhibitors based on bis([1, 2, 4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives as anticancer agents and apoptosis inducers.
Alsaif NA, Taghour MS, Alanazi MM, Obaidullah AJ, Al-Mehizia AA, Alanazi MM, Aldawas S, Elwan A, Elkady H. Alsaif NA, et al. Among authors: obaidullah aj. J Enzyme Inhib Med Chem. 2021 Dec;36(1):1093-1114. doi: 10.1080/14756366.2021.1915303. J Enzyme Inhib Med Chem. 2021. PMID: 34056992 Free PMC article.
64 results